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Discovery of Clinical Candidate BMS-906024: A Potent Pan-Notch Inhibitor for the Treatment of Leukemia and Solid Tumors.
Gavai, Ashvinikumar V; Quesnelle, Claude; Norris, Derek; Han, Wen-Ching; Gill, Patrice; Shan, Weifang; Balog, Aaron; Chen, Ke; Tebben, Andrew; Rampulla, Richard; Wu, Dauh-Rurng; Zhang, Yingru; Mathur, Arvind; White, Ronald; Rose, Anne; Wang, Haiqing; Yang, Zheng; Ranasinghe, Asoka; D'Arienzo, Celia; Guarino, Victor; Xiao, Lan; Su, Ching; Everlof, Gerry; Arora, Vinod; Shen, Ding Ren; Cvijic, Mary Ellen; Menard, Krista; Wen, Mei-Li; Meredith, Jere; Trainor, George; Lombardo, Louis J; Olson, Richard; Baran, Phil S; Hunt, John T; Vite, Gregory D; Fischer, Bruce S; Westhouse, Richard A; Lee, Francis Y.
Afiliação
  • Gavai AV; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Quesnelle C; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Norris D; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Han WC; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Gill P; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Shan W; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Balog A; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Chen K; Department of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
  • Tebben A; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Rampulla R; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Wu DR; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Zhang Y; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Mathur A; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • White R; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Rose A; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Wang H; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Yang Z; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Ranasinghe A; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • D'Arienzo C; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Guarino V; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Xiao L; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Su C; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Everlof G; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Arora V; Bristol-Myers Squibb Research and Development , 5 Research Parkway, Wallingford, Connecticut 06492, United States.
  • Shen DR; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Cvijic ME; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Menard K; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Wen ML; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Meredith J; Bristol-Myers Squibb Research and Development , 5 Research Parkway, Wallingford, Connecticut 06492, United States.
  • Trainor G; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Lombardo LJ; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Olson R; Bristol-Myers Squibb Research and Development , 5 Research Parkway, Wallingford, Connecticut 06492, United States.
  • Baran PS; Department of Chemistry, The Scripps Research Institute , 10550 North Torrey Pines Road, La Jolla, California 92037, United States.
  • Hunt JT; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Vite GD; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Fischer BS; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Westhouse RA; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
  • Lee FY; Bristol-Myers Squibb Research and Development , Princeton, New Jersey 08543, United States.
ACS Med Chem Lett ; 6(5): 523-7, 2015 May 14.
Article em En | MEDLINE | ID: mdl-26005526
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos