Hydrolytic metabolism of phenyl and benzyl salicylates, fragrances and flavoring agents in foods, by microsomes of rat and human tissues.

Ozaki, Hitomi; Sugihara, Kazumi; Tamura, Yuki; Fujino, Chieri; Watanabe, Yoko; Uramaru, Naoto; Sone, Tomomichi; Ohta, Shigeru; Kitamura, Shigeyuki

Ozaki, Hitomi; Sugihara, Kazumi; Tamura, Yuki; Fujino, Chieri; Watanabe, Yoko; Uramaru, Naoto; Sone, Tomomichi; Ohta, Shigeru; Kitamura, Shigeyuki.

Afiliação

Ozaki H; Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8553, Japan.
Sugihara K; Faculty of Pharmaceutical Science, Hiroshima International University, Koshingai 5-1-1, Kure, Hiroshima 737-0112, Japan.
Tamura Y; Nihon Pharmaceutical University, Komuro 10281, Ina-machi, Kitaadachi-gun, Saitama 362-0806, Japan.
Fujino C; Nihon Pharmaceutical University, Komuro 10281, Ina-machi, Kitaadachi-gun, Saitama 362-0806, Japan.
Watanabe Y; Nihon Pharmaceutical University, Komuro 10281, Ina-machi, Kitaadachi-gun, Saitama 362-0806, Japan.
Uramaru N; Nihon Pharmaceutical University, Komuro 10281, Ina-machi, Kitaadachi-gun, Saitama 362-0806, Japan.
Sone T; Faculty of Pharmaceutical Sciences, Setsunan University, Nagaotoge-cho 45-1, Hirakata, Osaka 573-0101, Japan.
Ohta S; Graduate School of Biomedical and Health Sciences, Hiroshima University, Kasumi 1-2-3, Minami-ku, Hiroshima 734-8553, Japan.
Kitamura S; Nihon Pharmaceutical University, Komuro 10281, Ina-machi, Kitaadachi-gun, Saitama 362-0806, Japan. Electronic address: kitamura@nichiyaku.ac.jp.

Food Chem Toxicol ; 86: 116-23, 2015 Dec.

Article em En | MEDLINE | ID: mdl-26321725

Assuntos

Aromatizantes/metabolismo; Microssomos/metabolismo; Salicilatos/metabolismo; Animais; Hidrolases de Éster Carboxílico/genética; Hidrolases de Éster Carboxílico/metabolismo; Aromatizantes/química; Humanos; Hidrólise; Intestino Delgado/metabolismo; Fígado/metabolismo; Masculino; Ratos; Ratos Sprague-Dawley; Salicilatos/química

Palavras-chave

Carboxylesterase; Human liver and small-intestinal microsomes; Hydrolytic metabolism; Rat tissue microsomes; Salicylate; Salicylic acid

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Salicilatos / Aromatizantes / Microssomos Limite: Animals / Humans / Male Idioma: En Revista: Food Chem Toxicol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido

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