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Disruption of in vivo Chronic Lymphocytic Leukemia Tumor-Microenvironment Interactions by Ibrutinib--Findings from an Investigator-Initiated Phase II Study.
Niemann, Carsten U; Herman, Sarah E M; Maric, Irina; Gomez-Rodriguez, Julio; Biancotto, Angelique; Chang, Betty Y; Martyr, Sabrina; Stetler-Stevenson, Maryalice; Yuan, Constance M; Calvo, Katherine R; Braylan, Raul C; Valdez, Janet; Lee, Yuh Shan; Wong, Deanna H; Jones, Jade; Sun, Clare; Marti, Gerald E; Farooqui, Mohammed Z H; Wiestner, Adrian.
Afiliação
  • Niemann CU; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland. Department of Hematology, Rigshospitalet, Copenhagen University Hospital, Denmark.
  • Herman SE; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  • Maric I; Department of Laboratory Medicine, Clinical Research Center, NIH, Bethesda, Maryland.
  • Gomez-Rodriguez J; National Human Genome Research Institute, NIH, Bethesda, Maryland.
  • Biancotto A; Center for Human Immunology, Autoimmunity and Inflammation, NIH, Bethesda, Maryland.
  • Chang BY; Pharmacyclics Inc., Sunnyvale, California.
  • Martyr S; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  • Stetler-Stevenson M; Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
  • Yuan CM; Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, Maryland.
  • Calvo KR; Department of Laboratory Medicine, Clinical Research Center, NIH, Bethesda, Maryland.
  • Braylan RC; Department of Laboratory Medicine, Clinical Research Center, NIH, Bethesda, Maryland.
  • Valdez J; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  • Lee YS; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  • Wong DH; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  • Jones J; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland. Medical Research Scholars Program, NIH, Bethesda, Maryland.
  • Sun C; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  • Marti GE; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  • Farooqui MZ; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland.
  • Wiestner A; Hematology Branch, National Heart, Lung, and Blood Institute, NIH, Bethesda, Maryland. wiestnea@nhlbi.nih.gov.
Clin Cancer Res ; 22(7): 1572-82, 2016 Apr 01.
Article em En | MEDLINE | ID: mdl-26660519

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Leucemia Linfocítica Crônica de Células B / Inibidores de Proteínas Quinases / Microambiente Tumoral / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged80 Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Dinamarca País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Leucemia Linfocítica Crônica de Células B / Inibidores de Proteínas Quinases / Microambiente Tumoral / Antineoplásicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Aged80 Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Dinamarca País de publicação: Estados Unidos