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Disrupting Hypoxia-Induced Bicarbonate Transport Acidifies Tumor Cells and Suppresses Tumor Growth.
McIntyre, Alan; Hulikova, Alzbeta; Ledaki, Ioanna; Snell, Cameron; Singleton, Dean; Steers, Graham; Seden, Peter; Jones, Dylan; Bridges, Esther; Wigfield, Simon; Li, Ji-Liang; Russell, Angela; Swietach, Pawel; Harris, Adrian L.
Afiliação
  • McIntyre A; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom. Cancer Biology, Division of Cancer and Stem Cells, University of Nottingham, Nottingham, United Kingdom.
  • Hulikova A; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
  • Ledaki I; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Snell C; Nuffield Department of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
  • Singleton D; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Steers G; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Seden P; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom. Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
  • Jones D; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Bridges E; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Wigfield S; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Li JL; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom.
  • Russell A; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Oxford, United Kingdom. Department of Pharmacology, University of Oxford, Oxford, United Kingdom.
  • Swietach P; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
  • Harris AL; Molecular Oncology Laboratories, Department of Oncology, University of Oxford, Weatherall Institute of Molecular Medicine, Oxford, United Kingdom. aharris.lab@imm.ox.ac.uk.
Cancer Res ; 76(13): 3744-55, 2016 07 01.
Article em En | MEDLINE | ID: mdl-27197160

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bicarbonatos / Hipóxia / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bicarbonatos / Hipóxia / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos