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A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation.
Stobart, Christopher C; Rostad, Christina A; Ke, Zunlong; Dillard, Rebecca S; Hampton, Cheri M; Strauss, Joshua D; Yi, Hong; Hotard, Anne L; Meng, Jia; Pickles, Raymond J; Sakamoto, Kaori; Lee, Sujin; Currier, Michael G; Moin, Syed M; Graham, Barney S; Boukhvalova, Marina S; Gilbert, Brian E; Blanco, Jorge C G; Piedra, Pedro A; Wright, Elizabeth R; Moore, Martin L.
Afiliação
  • Stobart CC; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Rostad CA; Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA.
  • Ke Z; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Dillard RS; Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA.
  • Hampton CM; School of Biology, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.
  • Strauss JD; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Yi H; Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA.
  • Hotard AL; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Meng J; Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA.
  • Pickles RJ; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Sakamoto K; Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA.
  • Lee S; Robert P Apkarian Integrated Electron Microscopy Core, Emory University, Atlanta, Georgia 30322, USA.
  • Currier MG; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Moin SM; Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA.
  • Graham BS; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Boukhvalova MS; Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA.
  • Gilbert BE; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.
  • Blanco JC; Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602, USA.
  • Piedra PA; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
  • Wright ER; Children's Healthcare of Atlanta, Atlanta, Georgia 30322, USA.
  • Moore ML; Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Nat Commun ; 7: 13916, 2016 12 21.
Article em En | MEDLINE | ID: mdl-28000669

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Atenuadas / Vírus Sincicial Respiratório Humano / Infecções por Vírus Respiratório Sincicial / Vacinas contra Vírus Sincicial Respiratório Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vacinas Atenuadas / Vírus Sincicial Respiratório Humano / Infecções por Vírus Respiratório Sincicial / Vacinas contra Vírus Sincicial Respiratório Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido