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Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.
Ludwig, Kerstin U; Böhmer, Anne C; Bowes, John; Nikolic, Milos; Ishorst, Nina; Wyatt, Niki; Hammond, Nigel L; Gölz, Lina; Thieme, Frederic; Barth, Sandra; Schuenke, Hannah; Klamt, Johanna; Spielmann, Malte; Aldhorae, Khalid; Rojas-Martinez, Augusto; Nöthen, Markus M; Rada-Iglesias, Alvaro; Dixon, Michael J; Knapp, Michael; Mangold, Elisabeth.
Afiliação
  • Ludwig KU; Institute of Human Genetics University of Bonn, Bonn 53127, Germany.
  • Böhmer AC; Department of Genomics, Life and Brain Center, University of Bonn, Bonn 53127, Germany.
  • Bowes J; Institute of Human Genetics University of Bonn, Bonn 53127, Germany.
  • Nikolic M; Department of Genomics, Life and Brain Center, University of Bonn, Bonn 53127, Germany.
  • Ishorst N; Arthritis Research UK Centre for Genetics and Genomics, The University of Manchester, Manchester M13 9PT, UK.
  • Wyatt N; Center for Molecular Medicine Cologne.
  • Hammond NL; Cologne Excellence Cluster for Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne 50931, Germany.
  • Gölz L; Institute of Human Genetics University of Bonn, Bonn 53127, Germany.
  • Thieme F; Department of Genomics, Life and Brain Center, University of Bonn, Bonn 53127, Germany.
  • Barth S; Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Schuenke H; Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Klamt J; Department of Orthodontics, University of Bonn, Bonn 53111, Germany.
  • Spielmann M; Institute of Human Genetics University of Bonn, Bonn 53127, Germany.
  • Aldhorae K; Department of Genomics, Life and Brain Center, University of Bonn, Bonn 53127, Germany.
  • Rojas-Martinez A; Institute of Human Genetics University of Bonn, Bonn 53127, Germany.
  • Nöthen MM; Department of Genomics, Life and Brain Center, University of Bonn, Bonn 53127, Germany.
  • Rada-Iglesias A; Institute of Human Genetics University of Bonn, Bonn 53127, Germany.
  • Dixon MJ; Department of Genomics, Life and Brain Center, University of Bonn, Bonn 53127, Germany.
  • Knapp M; Institute of Human Genetics University of Bonn, Bonn 53127, Germany.
  • Mangold E; Department of Genomics, Life and Brain Center, University of Bonn, Bonn 53127, Germany.
Hum Mol Genet ; 26(4): 829-842, 2017 02 15.
Article em En | MEDLINE | ID: mdl-28087736
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Humanos / Fenda Labial / Fissura Palatina / Polimorfismo de Nucleotídeo Único / Bases de Dados Genéticas / Estudo de Associação Genômica Ampla / Loci Gênicos Tipo de estudo: Etiology_studies / Risk_factors_studies / Systematic_reviews Limite: Animals / Female / Humans / Male Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromossomos Humanos / Fenda Labial / Fissura Palatina / Polimorfismo de Nucleotídeo Único / Bases de Dados Genéticas / Estudo de Associação Genômica Ampla / Loci Gênicos Tipo de estudo: Etiology_studies / Risk_factors_studies / Systematic_reviews Limite: Animals / Female / Humans / Male Idioma: En Revista: Hum Mol Genet Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido