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Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis.
McDonald, Oliver G; Li, Xin; Saunders, Tyler; Tryggvadottir, Rakel; Mentch, Samantha J; Warmoes, Marc O; Word, Anna E; Carrer, Alessandro; Salz, Tal H; Natsume, Sonoko; Stauffer, Kimberly M; Makohon-Moore, Alvin; Zhong, Yi; Wu, Hao; Wellen, Kathryn E; Locasale, Jason W; Iacobuzio-Donahue, Christine A; Feinberg, Andrew P.
Afiliação
  • McDonald OG; Department of Pathology, Microbiology and Immunology, Vanderbilt-Ingram Cancer Center, and Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Li X; Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Saunders T; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Tryggvadottir R; Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Mentch SJ; Duke Cancer Institute, Duke Molecular Physiology Institute, Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA.
  • Warmoes MO; Duke Cancer Institute, Duke Molecular Physiology Institute, Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA.
  • Word AE; Department of Pathology, Microbiology and Immunology, Vanderbilt-Ingram Cancer Center, and Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Carrer A; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
  • Salz TH; Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Natsume S; Department of Pathology, Microbiology and Immunology, Vanderbilt-Ingram Cancer Center, and Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Stauffer KM; Department of Pathology, Microbiology and Immunology, Vanderbilt-Ingram Cancer Center, and Epithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Makohon-Moore A; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Zhong Y; Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Wu H; Department of Biostatistics and Bioinformatics, Emory University, Atlanta, Georgia, USA.
  • Wellen KE; Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
  • Locasale JW; Duke Cancer Institute, Duke Molecular Physiology Institute, Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA.
  • Iacobuzio-Donahue CA; Departments of Pathology and Human Oncology and Pathogenesis Program, David M. Rubenstein Center for Pancreatic Cancer Research, Memorial Sloan Kettering Cancer Center, New York, New York, USA.
  • Feinberg AP; Center for Epigenetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Nat Genet ; 49(3): 367-376, 2017 Mar.
Article em En | MEDLINE | ID: mdl-28092686

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Epigênese Genética / Glucose / Metástase Neoplásica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Epigênese Genética / Glucose / Metástase Neoplásica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Genet Assunto da revista: GENETICA MEDICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos