Carboxymethyl ß-cyclodextrin as chiral selector in capillary electrophoresis: Enantioseparation of 16 basic chiral drugs and its chiral recognition mechanism associated with drugs' structural features.

Fang, Linlin; Du, Yueying; Hu, Xiaoyu; Luo, Linda; Guo, Xin; Guo, Xingjie; Yu, Jia

Fang, Linlin; Du, Yueying; Hu, Xiaoyu; Luo, Linda; Guo, Xin; Guo, Xingjie; Yu, Jia.

Afiliação

Fang L; Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning Province, People's Republic of China.
Du Y; Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning Province, People's Republic of China.
Hu X; Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning Province, People's Republic of China.
Luo L; Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning Province, People's Republic of China.
Guo X; Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning Province, People's Republic of China.
Guo X; Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning Province, People's Republic of China.
Yu J; Department of Pharmaceutical Analysis, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning Province, People's Republic of China.

Biomed Chromatogr ; 31(11)2017 Nov.

Article em En | MEDLINE | ID: mdl-28431453

Assuntos

Eletroforese Capilar/métodos; Propanolaminas/química; Propanolaminas/isolamento & purificação; beta-Ciclodextrinas/química; Broncodilatadores/análise; Broncodilatadores/química; Broncodilatadores/isolamento & purificação; Fármacos Cardiovasculares/análise; Fármacos Cardiovasculares/química; Fármacos Cardiovasculares/isolamento & purificação; Limite de Detecção; Modelos Lineares; Propanolaminas/análise; Reprodutibilidade dos Testes; Estereoisomerismo

Palavras-chave

capillary electrophoresis; carboxymethyl-ß-cyclodextrin; enantiomeric purity determination; enantiomeric separation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Propanolaminas / Eletroforese Capilar / Beta-Ciclodextrinas Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Biomed Chromatogr Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido

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