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Disruption of drug-resistant biofilms using de novo designed short α-helical antimicrobial peptides with idealized facial amphiphilicity.
Khara, Jasmeet Singh; Obuobi, Sybil; Wang, Ying; Hamilton, Melissa Shea; Robertson, Brian D; Newton, Sandra M; Yang, Yi Yan; Langford, Paul R; Ee, Pui Lai Rachel.
Afiliação
  • Khara JS; Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore; Section of Paediatrics, Department of Medicine, St Mary's Campus, Imperial College London, London W2 1PG, United Kingdom; MRC Centre for Molecular Bacteriology and Infection, Department of Medi
  • Obuobi S; Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore.
  • Wang Y; Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore.
  • Hamilton MS; Section of Paediatrics, Department of Medicine, St Mary's Campus, Imperial College London, London W2 1PG, United Kingdom.
  • Robertson BD; MRC Centre for Molecular Bacteriology and Infection, Department of Medicine, Imperial College London, London SW7 2AZ, United Kingdom.
  • Newton SM; Section of Paediatrics, Department of Medicine, St Mary's Campus, Imperial College London, London W2 1PG, United Kingdom.
  • Yang YY; Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, Singapore 138669, Singapore.
  • Langford PR; Section of Paediatrics, Department of Medicine, St Mary's Campus, Imperial College London, London W2 1PG, United Kingdom.
  • Ee PLR; Department of Pharmacy, National University of Singapore, 18 Science Drive 4, Singapore 117543, Singapore. Electronic address: phaeplr@nus.edu.sg.
Acta Biomater ; 57: 103-114, 2017 07 15.
Article em En | MEDLINE | ID: mdl-28457962

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Biofilmes / Peptídeos Catiônicos Antimicrobianos / Farmacorresistência Bacteriana / Endotoxinas Idioma: En Revista: Acta Biomater Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bactérias / Biofilmes / Peptídeos Catiônicos Antimicrobianos / Farmacorresistência Bacteriana / Endotoxinas Idioma: En Revista: Acta Biomater Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido