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Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers.
Kuchenbaecker, Karoline B; Hopper, John L; Barnes, Daniel R; Phillips, Kelly-Anne; Mooij, Thea M; Roos-Blom, Marie-José; Jervis, Sarah; van Leeuwen, Flora E; Milne, Roger L; Andrieu, Nadine; Goldgar, David E; Terry, Mary Beth; Rookus, Matti A; Easton, Douglas F; Antoniou, Antonis C; McGuffog, Lesley; Evans, D Gareth; Barrowdale, Daniel; Frost, Debra; Adlard, Julian; Ong, Kai-Ren; Izatt, Louise; Tischkowitz, Marc; Eeles, Ros; Davidson, Rosemarie; Hodgson, Shirley; Ellis, Steve; Nogues, Catherine; Lasset, Christine; Stoppa-Lyonnet, Dominique; Fricker, Jean-Pierre; Faivre, Laurence; Berthet, Pascaline; Hooning, Maartje J; van der Kolk, Lizet E; Kets, Carolien M; Adank, Muriel A; John, Esther M; Chung, Wendy K; Andrulis, Irene L; Southey, Melissa; Daly, Mary B; Buys, Saundra S; Osorio, Ana; Engel, Christoph; Kast, Karin; Schmutzler, Rita K; Caldes, Trinidad; Jakubowska, Anna; Simard, Jacques.
Afiliação
  • Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England2Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, England.
  • Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population Health, University of Melbourne, Melbourne, Australia.
  • Barnes DR; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.
  • Phillips KA; Centre for Epidemiology and Biostatistics, Melbourne School of Population Health, University of Melbourne, Melbourne, Australia4Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia5Department of Medicine, St Vincent's Hospital, University of Melbourne, Parkville, Australi
  • Mooij TM; Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Roos-Blom MJ; Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands8Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
  • Jervis S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England9Mathematics Institute, University of Warwick, Coventry, England.
  • van Leeuwen FE; Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Milne RL; Centre for Epidemiology and Biostatistics, Melbourne School of Population Health, University of Melbourne, Melbourne, Australia10Cancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, Australia.
  • Andrieu N; Inserm U900, Paris, France12Institut Curie, Paris, France13Mines ParisTech, Fontainebleau, France14PSL Research University, Paris, France.
  • Goldgar DE; Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah.
  • Terry MB; Department of Epidemiology, Columbia University, New York, New York.
  • Rookus MA; Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.
  • Antoniou AC; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.
  • McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.
  • Evans DG; Genomic Medicine, Manchester Academic Health Sciences Centre, Institute of Human Development, Manchester University, Central Manchester University Hospitals NHS Foundation Trust, Manchester, England.
  • Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.
  • Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.
  • Adlard J; Yorkshire Regional Genetics Service, Chapel Allerton Hospital, Leeds, England.
  • Ong KR; West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Birmingham, England.
  • Izatt L; Clinical Genetics, Guy's and St Thomas' NHS Foundation Trust, London, England.
  • Tischkowitz M; Department of Medical Genetics and National Institute for Health Research Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, England.
  • Eeles R; Oncogenetics Team, Institute of Cancer Research and Royal Marsden NHS Foundation Trust, Sutton, England.
  • Davidson R; Department of Clinical Genetics, South Glasgow University Hospitals, Glasgow, Scotland.
  • Hodgson S; Department of Clinical Genetics, St George's, University of London, London, England.
  • Ellis S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, England.
  • Nogues C; Oncogénétique Clinique, Hôpital René Huguenin/Institut Curie, Saint-Cloud, France.
  • Lasset C; Unité de Prévention et d'Epidémiologie Génétique, Centre Léon Bérard, Lyon, France.
  • Stoppa-Lyonnet D; Institut Curie, Department of Tumour Biology, Paris, France28Institut Curie, INSERM U830, Paris, France29Université Paris Descartes, Sorbonne Paris Cité, Paris, France.
  • Fricker JP; Unité d'Oncogénétique, Centre Paul Strauss, Strasbourg, France.
  • Faivre L; Centre de Lutte Contre le Cancer Georges François Leclerc, Dijon, France32Centre de Génétique, Hôpital d'Enfants, CHU Dijon, Dijon, France.
  • Berthet P; Centre François Baclesse, Caen, France.
  • Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • van der Kolk LE; Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Kets CM; Department of Human Genetics, Radboud University Medical Center, Nijmegen, the Netherlands.
  • Adank MA; Department of Clinical Genetics, VU University Medical Center, Amsterdam, the Netherlands.
  • John EM; Department of Epidemiology, Cancer Prevention Institute of California, Fremont.
  • Chung WK; Departments of Pedicatrics and Medicine, Columbia University, New York, New York.
  • Andrulis IL; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada41Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.
  • Southey M; Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia.
  • Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
  • Buys SS; Department of Medicine, Huntsman Cancer Institute, Salt Lake City, Utah.
  • Osorio A; Human Genetics Group, Spanish National Cancer Centre, Madrid, Spain46Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain.
  • Engel C; Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany48LIFE-Leipzig Research Centre for Civilization Diseases, University of Leipzig, Leipzig, Germany.
  • Kast K; Department of Gynaecology and Obstetrics, University Hospital Carl Gustav Carus, Dresden, Germany50National Center for Tumor Diseases, Partner Site Dresden, Dresden, Germany51German Cancer Consortium, Dresden and German Cancer Research Center, Heidelberg, Germany.
  • Schmutzler RK; Center for Familial Breast and Ovarian Cancer, Center for Integrated Oncology, Medical Faculty, University of Cologne and University Hospital Cologne, Cologne, Germany.
  • Caldes T; Molecular Oncology Laboratory, Hospital Clinico San Carlos, Instituto de Investigación Sanitaria San Carlos, Madrid, Spain.
  • Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland.
  • Simard J; Genomics Center, Centre Hospitalier Universitaire de Québec Research Center and Laval University, Québec City, Québec, Canada.
JAMA ; 317(23): 2402-2416, 2017 06 20.
Article em En | MEDLINE | ID: mdl-28632866
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias da Mama / Segunda Neoplasia Primária / Genes BRCA1 / Genes BRCA2 / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: JAMA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Neoplasias da Mama / Segunda Neoplasia Primária / Genes BRCA1 / Genes BRCA2 / Mutação Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Revista: JAMA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos