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Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence.
Glück, Selene; Guey, Baptiste; Gulen, Muhammet Fatih; Wolter, Katharina; Kang, Tae-Won; Schmacke, Niklas Arndt; Bridgeman, Anne; Rehwinkel, Jan; Zender, Lars; Ablasser, Andrea.
Afiliação
  • Glück S; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
  • Guey B; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
  • Gulen MF; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
  • Wolter K; Department of Internal Medicine VIII, University Hospital Tübingen, 72076 Tübingen, Germany.
  • Kang TW; Department of Physiology I, Institute of Physiology, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
  • Schmacke NA; Department of Internal Medicine VIII, University Hospital Tübingen, 72076 Tübingen, Germany.
  • Bridgeman A; Department of Physiology I, Institute of Physiology, Eberhard Karls University Tübingen, 72076 Tübingen, Germany.
  • Rehwinkel J; Translational Gastrointestinal Oncology Group, German Consortium for Translational Cancer Research (DKTK), German Cancer Research Center (DKFZ), Heidelberg 69120, Germany.
  • Zender L; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
  • Ablasser A; Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, UK.
Nat Cell Biol ; 19(9): 1061-1070, 2017 Sep.
Article em En | MEDLINE | ID: mdl-28759028

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Senescência Celular / Citosol / Imunidade Inata / Nucleotidiltransferases Limite: Animals Idioma: En Revista: Nat Cell Biol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cromatina / Senescência Celular / Citosol / Imunidade Inata / Nucleotidiltransferases Limite: Animals Idioma: En Revista: Nat Cell Biol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suíça País de publicação: Reino Unido