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Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).
Sangwan, Smriti; Zhao, Anni; Adams, Katrina L; Jayson, Christina K; Sawaya, Michael R; Guenther, Elizabeth L; Pan, Albert C; Ngo, Jennifer; Moore, Destaye M; Soriaga, Angela B; Do, Thanh D; Goldschmidt, Lukasz; Nelson, Rebecca; Bowers, Michael T; Koehler, Carla M; Shaw, David E; Novitch, Bennett G; Eisenberg, David S.
Afiliação
  • Sangwan S; Howard Hughes Medical Institute, UCLA-DOE and Molecular Biology Institutes, Department of Biological Chemistry, University of California, Los Angeles, CA 90095.
  • Zhao A; Howard Hughes Medical Institute, UCLA-DOE and Molecular Biology Institutes, Department of Biological Chemistry, University of California, Los Angeles, CA 90095.
  • Adams KL; Department of Neurobiology, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095.
  • Jayson CK; Department of Chemistry & Biochemistry, University of California, Los Angeles, CA 90095.
  • Sawaya MR; Howard Hughes Medical Institute, UCLA-DOE and Molecular Biology Institutes, Department of Biological Chemistry, University of California, Los Angeles, CA 90095.
  • Guenther EL; Howard Hughes Medical Institute, UCLA-DOE and Molecular Biology Institutes, Department of Biological Chemistry, University of California, Los Angeles, CA 90095.
  • Pan AC; D. E. Shaw Research, New York, NY 10036.
  • Ngo J; Department of Chemistry & Biochemistry, University of California, Los Angeles, CA 90095.
  • Moore DM; Department of Neurobiology, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095.
  • Soriaga AB; Howard Hughes Medical Institute, UCLA-DOE and Molecular Biology Institutes, Department of Biological Chemistry, University of California, Los Angeles, CA 90095.
  • Do TD; Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106.
  • Goldschmidt L; Howard Hughes Medical Institute, UCLA-DOE and Molecular Biology Institutes, Department of Biological Chemistry, University of California, Los Angeles, CA 90095.
  • Nelson R; Howard Hughes Medical Institute, UCLA-DOE and Molecular Biology Institutes, Department of Biological Chemistry, University of California, Los Angeles, CA 90095.
  • Bowers MT; Department of Chemistry and Biochemistry, University of California, Santa Barbara, CA 93106.
  • Koehler CM; Department of Chemistry & Biochemistry, University of California, Los Angeles, CA 90095.
  • Shaw DE; D. E. Shaw Research, New York, NY 10036.
  • Novitch BG; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032.
  • Eisenberg DS; Department of Neurobiology, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095.
Proc Natl Acad Sci U S A ; 114(33): 8770-8775, 2017 08 15.
Article em En | MEDLINE | ID: mdl-28760994

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superóxido Dismutase-1 / Esclerose Lateral Amiotrófica Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Superóxido Dismutase-1 / Esclerose Lateral Amiotrófica Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos