Synthesis, spectroscopic characterization and in vitro anticancer activity of new platinum(II) complexes with some thione ligands in the presence of triethylphosphine.

Jomaa, Mohammed Yagoub; Altaf, Muhammed; Ahmad, Saeed; Bhatia, Gaurav; Singh, Jatinder; Altuwaijri, Saleh; Isab, Anvarhusein A

Synthesis, spectroscopic characterization and in vitro anticancer activity of new platinum(II) complexes with some thione ligands in the presence of triethylphosphine.

Jomaa, Mohammed Yagoub; Altaf, Muhammed; Ahmad, Saeed; Bhatia, Gaurav; Singh, Jatinder; Altuwaijri, Saleh; Isab, Anvarhusein A.

Afiliação

Jomaa MY; Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, 31261, Saudi Arabia.
Altaf M; Center of Research Excellence in Nanotechnology, King Fahd University of Petroleum & Minerals, Dhahran, 31261, Saudi Arabia.
Ahmad S; Department of Chemistry, College of Sciences and Humanities, Prince Sattam bin Abdulaziz University, Al-Kharj, 11942, Saudi Arabia.
Bhatia G; Department of Molecular, Biology & Biochemistry, Guru Nanak Dev University, Amritsar, 143005, India.
Singh J; Department of Molecular, Biology & Biochemistry, Guru Nanak Dev University, Amritsar, 143005, India.
Altuwaijri S; Clinical Research Laboratory, SAAD Research Development Center, SAAD Specialist Hospital, Al-Khobar, 31952, Saudi Arabia.
Isab AA; Department of Chemistry, King Fahd University of Petroleum and Minerals, Dhahran, 31261, Saudi Arabia. aisab@kfupm.edu.sa.

Biometals ; 30(5): 787-795, 2017 Oct.

Article em En | MEDLINE | ID: mdl-28986698

Assuntos

Antineoplásicos/síntese química; Compostos Organoplatínicos/síntese química; Fosfinas/química; Tionas/química; Células A549; Antineoplásicos/farmacologia; Carboplatina/farmacologia; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; Cisplatino/farmacologia; Células HeLa; Humanos; Concentração Inibidora 50; Ligantes; Células MCF-7; Compostos Organoplatínicos/farmacologia; Relação Estrutura-Atividade

Palavras-chave

Anti-cancer activity; Cancer cell lines; Pt(II) complexes; Thione ligands

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organoplatínicos / Fosfinas / Tionas / Antineoplásicos Limite: Humans Idioma: En Revista: Biometals Assunto da revista: BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Arábia Saudita País de publicação: Holanda

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