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Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice.
Devoy, Anny; Kalmar, Bernadett; Stewart, Michelle; Park, Heesoon; Burke, Beverley; Noy, Suzanna J; Redhead, Yushi; Humphrey, Jack; Lo, Kitty; Jaeger, Julian; Mejia Maza, Alan; Sivakumar, Prasanth; Bertolin, Cinzia; Soraru, Gianni; Plagnol, Vincent; Greensmith, Linda; Acevedo Arozena, Abraham; Isaacs, Adrian M; Davies, Benjamin; Fratta, Pietro; Fisher, Elizabeth M C.
Afiliação
  • Devoy A; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Kalmar B; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Stewart M; The Mary Lyon Centre, MRC Harwell Institute, Harwell, Oxfordshire OX11 0RD, UK.
  • Park H; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Burke B; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Noy SJ; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Redhead Y; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Humphrey J; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Lo K; UCL Genetics Institute, Gower Street, London WC1E 6BT, UK.
  • Jaeger J; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Mejia Maza A; UCL Genetics Institute, Gower Street, London WC1E 6BT, UK.
  • Sivakumar P; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Bertolin C; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Soraru G; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Plagnol V; Department of Neurosciences, Università degli Studi di Padova, 35121 Padova, Italy.
  • Greensmith L; Department of Neurosciences, Università degli Studi di Padova, 35121 Padova, Italy.
  • Acevedo Arozena A; UCL Genetics Institute, Gower Street, London WC1E 6BT, UK.
  • Isaacs AM; Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Davies B; MRC Center for Neuromuscular Diseases, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.
  • Fratta P; The Mary Lyon Centre, MRC Harwell Institute, Harwell, Oxfordshire OX11 0RD, UK.
  • Fisher EMC; Hospital Universitario de Canarias, Fundación Canaria de Investigación Sanitaria, Tenerife, Canary Islands, Spain.
Brain ; 140(11): 2797-2805, 2017 Nov 01.
Article em En | MEDLINE | ID: mdl-29053787
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutação da Fase de Leitura / Proteína FUS de Ligação a RNA / Modelos Animais de Doenças / Agregação Patológica de Proteínas / Esclerose Lateral Amiotrófica / Camundongos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Brain Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Mutação da Fase de Leitura / Proteína FUS de Ligação a RNA / Modelos Animais de Doenças / Agregação Patológica de Proteínas / Esclerose Lateral Amiotrófica / Camundongos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Brain Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido