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Drug repurposing screening identifies bortezomib and panobinostat as drugs targeting cancer associated fibroblasts (CAFs) by synergistic induction of apoptosis.
Lee, Hak-Min; Lee, Eunmyong; Yeo, So-Young; Shin, Sang; Park, Hyun-Kyu; Nam, Do-Hyun; Kim, Seok-Hyung.
Afiliação
  • Lee HM; Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
  • Lee E; Department of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea.
  • Yeo SY; Samsung Biomedical Research Institute, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
  • Shin S; Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
  • Park HK; Department of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea.
  • Nam DH; Department of Health Science and Technology, Samsung Advanced Institute for Health Science and Technology, Sungkyunkwan University, Seoul, Republic of Korea.
  • Kim SH; Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Invest New Drugs ; 36(4): 545-560, 2018 08.
Article em En | MEDLINE | ID: mdl-29349597
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Bortezomib / Fibroblastos Associados a Câncer / Panobinostat Tipo de estudo: Diagnostic_studies / Risk_factors_studies / Screening_studies Limite: Animals / Female / Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Apoptose / Bortezomib / Fibroblastos Associados a Câncer / Panobinostat Tipo de estudo: Diagnostic_studies / Risk_factors_studies / Screening_studies Limite: Animals / Female / Humans Idioma: En Revista: Invest New Drugs Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos