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Identification of influenza polymerase inhibitors targeting C-terminal domain of PA through surface plasmon resonance screening.
Lo, Chun-Yeung; Li, Olive Tin-Wai; Tang, Wen-Ping; Hu, Chun; Wang, Guo Xin; Ngo, Jacky Chi-Ki; Wan, David Chi-Cheong; Poon, Leo Lit-Man; Shaw, Pang-Chui.
Afiliação
  • Lo CY; Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
  • Li OT; Centre of Influenza Research, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Shatin, Hong Kong SAR, China.
  • Tang WP; The School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China.
  • Hu C; The School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China.
  • Wang GX; Research Center of Plasmonic and Near-Infrared Science, Research Institute of Tsinghua University in Shenzhen, Shenzhen, China.
  • Ngo JC; Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
  • Wan DC; School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China.
  • Poon LL; Centre of Influenza Research, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Shatin, Hong Kong SAR, China.
  • Shaw PC; Centre for Protein Science and Crystallography, School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China. pcshaw@cuhk.edu.hk.
Sci Rep ; 8(1): 2280, 2018 02 02.
Article em En | MEDLINE | ID: mdl-29396435
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Influenza A / Proteínas Virais / RNA Polimerase Dependente de RNA / Ressonância de Plasmônio de Superfície / Avaliação Pré-Clínica de Medicamentos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Influenza A / Proteínas Virais / RNA Polimerase Dependente de RNA / Ressonância de Plasmônio de Superfície / Avaliação Pré-Clínica de Medicamentos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido