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AP2σ Mutations Impair Calcium-Sensing Receptor Trafficking and Signaling, and Show an Endosomal Pathway to Spatially Direct G-Protein Selectivity.
Gorvin, Caroline M; Rogers, Angela; Hastoy, Benoit; Tarasov, Andrei I; Frost, Morten; Sposini, Silvia; Inoue, Asuka; Whyte, Michael P; Rorsman, Patrik; Hanyaloglu, Aylin C; Breitwieser, Gerda E; Thakker, Rajesh V.
Afiliação
  • Gorvin CM; Academic Endocrine Unit, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK; Centre for Endocrinology, Diabetes and Metabolism (CEDAM), Birmingham Health Partners, Birmingham, UK.
  • Rogers A; Academic Endocrine Unit, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Hastoy B; Diabetes Research Laboratory, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Tarasov AI; Diabetes Research Laboratory, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Frost M; Academic Endocrine Unit, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Sposini S; Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College London, London, UK.
  • Inoue A; Laboratory of Molecular and Cellular Biochemistry, Tohoku University, Sendai, Japan; Japan Science and Technology (JST) Agency, Precursory Research for Embryonic Science and Technology (PRESTO), Kawaguchi, Japan.
  • Whyte MP; Center for Metabolic Bone Disease and Molecular Research, Shriners Hospitals for Children, St. Louis, MO, USA.
  • Rorsman P; Diabetes Research Laboratory, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
  • Hanyaloglu AC; Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College London, London, UK.
  • Breitwieser GE; Geisinger Clinic, Weis Center for Research, Department of Functional and Molecular Genomics, Danville, PA, USA.
  • Thakker RV; Academic Endocrine Unit, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. Electronic address: rajesh.thakker@ndm.ox.ac.uk.
Cell Rep ; 22(4): 1054-1066, 2018 01 23.
Article em En | MEDLINE | ID: mdl-29420171
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endossomos / Proteínas de Ligação ao GTP / Sinalização do Cálcio / Complexo 2 de Proteínas Adaptadoras / Subunidades alfa do Complexo de Proteínas Adaptadoras / Receptores de Detecção de Cálcio Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Endossomos / Proteínas de Ligação ao GTP / Sinalização do Cálcio / Complexo 2 de Proteínas Adaptadoras / Subunidades alfa do Complexo de Proteínas Adaptadoras / Receptores de Detecção de Cálcio Limite: Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos