Teixobactin analogues reveal enduracididine to be non-essential for highly potent antibacterial activity and lipid II binding.

Parmar, Anish; Iyer, Abhishek; Prior, Stephen H; Lloyd, Daniel G; Leng Goh, Eunice Tze; Vincent, Charlotte S; Palmai-Pallag, Timea; Bachrati, Csanad Z; Breukink, Eefjan; Madder, Annemieke; Lakshminarayanan, Rajamani; Taylor, Edward J; Singh, Ishwar

Parmar, Anish; Iyer, Abhishek; Prior, Stephen H; Lloyd, Daniel G; Leng Goh, Eunice Tze; Vincent, Charlotte S; Palmai-Pallag, Timea; Bachrati, Csanad Z; Breukink, Eefjan; Madder, Annemieke; Lakshminarayanan, Rajamani; Taylor, Edward J; Singh, Ishwar.

Afiliação

Parmar A; School of Pharmacy , University of Lincoln , JBL Building, Beevor St. , Lincoln LN67DL , UK . Email: isingh@lincoln.ac.uk.
Iyer A; School of Pharmacy , University of Lincoln , JBL Building, Beevor St. , Lincoln LN67DL , UK . Email: isingh@lincoln.ac.uk.
Prior SH; Organic and Biomimetic Chemistry Research Group , Department of Organic and Macromolecular Chemistry , Ghent University , Krijgslaan 281 (S4) , B-9000 Ghent , Belgium.
Lloyd DG; School of Chemistry , University of Lincoln , JBL Building, Beevor St. , Lincoln LN67DL , UK.
Leng Goh ET; School of Life Sciences , University of Lincoln , JBL Building, Beevor St. , Lincoln LN67DL , UK.
Vincent CS; Singapore Eye Research Institute , The Academia, Discovery Tower Level 6, 20 College Road , Singapore 169857.
Palmai-Pallag T; School of Life Sciences , University of Lincoln , JBL Building, Beevor St. , Lincoln LN67DL , UK.
Bachrati CZ; School of Life Sciences , University of Lincoln , JBL Building, Beevor St. , Lincoln LN67DL , UK.
Breukink E; School of Life Sciences , University of Lincoln , JBL Building, Beevor St. , Lincoln LN67DL , UK.
Madder A; Department of Membrane Biochemistry and Biophysics , Institute of Biomembranes , Utrecht University , Padualaan 8 , 3584 CH Utrecht , The Netherlands.
Lakshminarayanan R; Organic and Biomimetic Chemistry Research Group , Department of Organic and Macromolecular Chemistry , Ghent University , Krijgslaan 281 (S4) , B-9000 Ghent , Belgium.
Taylor EJ; Singapore Eye Research Institute , The Academia, Discovery Tower Level 6, 20 College Road , Singapore 169857.
Singh I; School of Life Sciences , University of Lincoln , JBL Building, Beevor St. , Lincoln LN67DL , UK.

Chem Sci ; 8(12): 8183-8192, 2017 Dec 01.

Article em En | MEDLINE | ID: mdl-29568465

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Chem Sci Ano de publicação: 2017 Tipo de documento: Article País de publicação: Reino Unido

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