A cytotoxicity, optical spectroscopy and computational binding analysis of 4-[3-acetyl-5-(acetylamino)-2-methyl-2,3-dihydro-1,3,4-thiadiazole-2-yl]phenyl benzoate in calf thymus DNA.

Karthikeyan, Subramani; Bharanidharan, Ganesan; Mangaiyarkarasi, Rajendiran; Chinnathambi, Shanmugavel; Sriram, Ragavan; Gunasekaran, Krishnaswamy; Saravanan, Kandasamy; Gopikrishnan, Mani; Aruna, Prakasarao; Ganesan, Singaravelu

Karthikeyan, Subramani; Bharanidharan, Ganesan; Mangaiyarkarasi, Rajendiran; Chinnathambi, Shanmugavel; Sriram, Ragavan; Gunasekaran, Krishnaswamy; Saravanan, Kandasamy; Gopikrishnan, Mani; Aruna, Prakasarao; Ganesan, Singaravelu.

Afiliação

Karthikeyan S; Department of Medical Physics, Anna University, Chennai, India.
Bharanidharan G; Department of Medical Physics, Anna University, Chennai, India.
Mangaiyarkarasi R; Department of Medical Physics, Anna University, Chennai, India.
Chinnathambi S; Nanotechnology Innovation Station, National Institute for Materials Science, Tsukuba, Ibaraki, Japan.
Sriram R; Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Chennai, India.
Gunasekaran K; Centre of Advanced Study in Crystallography and Biophysics, University of Madras, Chennai, India.
Saravanan K; Department of Physics, Periyar University, Salem, India.
Gopikrishnan M; Department of Biochemistry, University of Madras, Chennai, India.
Aruna P; Department of Medical Physics, Anna University, Chennai, India.
Ganesan S; Department of Medical Physics, Anna University, Chennai, India.

Luminescence ; 33(4): 731-741, 2018 Jun.

Article em En | MEDLINE | ID: mdl-29578306

Assuntos

Antineoplásicos/farmacologia; Benzoatos/farmacologia; DNA/química; Tiadiazóis/farmacologia; Antineoplásicos/síntese química; Antineoplásicos/química; Benzoatos/química; Proliferação de Células/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Cristalografia por Raios X; Ensaios de Seleção de Medicamentos Antitumorais; Humanos; Modelos Moleculares; Teoria Quântica; Espectrometria de Fluorescência; Espectrofotometria Ultravioleta; Tiadiazóis/química; Células Tumorais Cultivadas

Palavras-chave

FRET; fluorescence spectroscopy; molecular docking; molecular dynamics; time resolved emission spectroscopy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiadiazóis / Benzoatos / DNA / Antineoplásicos Limite: Humans Idioma: En Revista: Luminescence Assunto da revista: BIOFISICA / BIOQUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Índia País de publicação: Reino Unido

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