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A rare variant in MLKL confers susceptibility to ApoE ɛ4-negative Alzheimer's disease in Hong Kong Chinese population.
Wang, Binbin; Bao, Suying; Zhang, Zhigang; Zhou, Xueya; Wang, Jing; Fan, Yanhui; Zhang, Yan; Li, Yan; Chen, Luhua; Jia, Yizhen; Li, Jiang; Li, Miaoxin; Zheng, Wenhua; Mu, Nan; Wang, Liqiu; Yu, Zhe; Wong, Dana S M; Zhang, Yalun; Kwan, Joseph; Ka-Fung Mak, Henry; Ambalavanan, Amirthagowri; Zhou, Sirui; Cai, Wangwei; Zheng, Jin; Huang, Shishu; Rouleau, Guy A; Yang, Wanling; Rogaeva, Ekaterina; Ma, Xu; St George-Hyslop, Peter; Chu, Leung Wing; Song, You-Qiang.
Afiliação
  • Wang B; Department of Genetics, National Research Institute for Family Planning, Beijing, China; Graduate School of Peking Union Medical College, Beijing, China.
  • Bao S; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Zhang Z; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Zhou X; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Wang J; Department of Genetics, National Research Institute for Family Planning, Beijing, China.
  • Fan Y; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Zhang Y; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China.
  • Li Y; Center for Transport Phenomena, Energy Research Institute of Shandong Academy of Sciences, Jinan, Shandong, China.
  • Chen L; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Jia Y; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Li J; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Li M; Department of Medical Genetics, Center for Genome Research, Center for Precision Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
  • Zheng W; The Faculty of Health Sciences, The University of Macau, Macau, China.
  • Mu N; Guangzhou Brain Hospital, Guangzhou, China.
  • Wang L; Department of Mechanical Engineering, The University of Hong Kong, Hong Kong, China.
  • Yu Z; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Wong DSM; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China.
  • Zhang Y; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
  • Kwan J; Department of Medicine, The University of Hong Kong, Hong Kong, China.
  • Ka-Fung Mak H; Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, China.
  • Ambalavanan A; Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada.
  • Zhou S; Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada.
  • Cai W; Department of Biochemistry and Molecular Biology, Hainan Medical College, Haikou, Hainan, China.
  • Zheng J; Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai, China.
  • Huang S; Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China.
  • Rouleau GA; Montreal Neurological Institute and Hospital, McGill University, Montréal, QC, Canada.
  • Yang W; Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China.
  • Rogaeva E; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
  • Ma X; Department of Genetics, National Research Institute for Family Planning, Beijing, China; Graduate School of Peking Union Medical College, Beijing, China. Electronic address: Nicgr@263.net.
  • St George-Hyslop P; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada; Department of Clinical Neurosciences, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
  • Chu LW; Department of Medicine, The University of Hong Kong, Hong Kong, China. Electronic address: lwchu@hku.hk.
  • Song YQ; School of Biomedical Sciences, The University of Hong Kong, Hong Kong, China; Centre for Genome Sciences, The University of Hong Kong, Hong Kong, China; State Key Laboratory for Cognitive and Brain Sciences, The University of Hong Kong, Hong Kong, China; HKU-SIRI/ZIRI, The University of Hong Kong, H
Neurobiol Aging ; 68: 160.e1-160.e7, 2018 08.
Article em En | MEDLINE | ID: mdl-29656768

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Variação Genética / Predisposição Genética para Doença / Estudos de Associação Genética / Doença de Alzheimer / Mutação com Perda de Função Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Neurobiol Aging Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Variação Genética / Predisposição Genética para Doença / Estudos de Associação Genética / Doença de Alzheimer / Mutação com Perda de Função Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Neurobiol Aging Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos