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Human carbonic anhydrase-8 AAV8 gene therapy inhibits nerve growth factor signaling producing prolonged analgesia and anti-hyperalgesia in mice.
Zhuang, Gerald Z; Upadhyay, Udita; Tong, Xiaoying; Kang, Yuan; Erasso, Diana M; Fu, Eugene S; Sarantopoulos, Konstantinos D; Martin, Eden R; Wiltshire, Tim; Diatchenko, Luda; Smith, Shad B; Maixner, William; Levitt, Roy C.
Afiliação
  • Zhuang GZ; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Upadhyay U; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Tong X; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Kang Y; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Erasso DM; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Fu ES; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Sarantopoulos KD; Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Martin ER; Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Wiltshire T; John T. MacDonald Foundation, Department of Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Diatchenko L; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
  • Smith SB; Department of Pharmacology and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA.
  • Maixner W; Alan Edwards Centre for Research on Pain, Department of Anesthesiology, McGill University, Montreal, Quebec, Canada.
  • Levitt RC; Center for Translational Pain Medicine, Department of Anesthesiology, Duke University School of Medicine, Durham, NC, USA.
Gene Ther ; 25(4): 297-311, 2018 07.
Article em En | MEDLINE | ID: mdl-29789638
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Genética / Biomarcadores Tumorais / Fator de Crescimento Neural / Receptores de Inositol 1,4,5-Trifosfato / Hiperalgesia Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Gene Ther Assunto da revista: GENETICA MEDICA / TERAPEUTICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Genética / Biomarcadores Tumorais / Fator de Crescimento Neural / Receptores de Inositol 1,4,5-Trifosfato / Hiperalgesia Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Gene Ther Assunto da revista: GENETICA MEDICA / TERAPEUTICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido