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Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy.
Blain, Alison M; Greally, Elizabeth; McClorey, Graham; Manzano, Raquel; Betts, Corinne A; Godfrey, Caroline; O'Donovan, Liz; Coursindel, Thibault; Gait, Mike J; Wood, Matthew J; MacGowan, Guy A; Straub, Volker W.
Afiliação
  • Blain AM; Institute of Genetic Medicine, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, United Kingdom.
  • Greally E; Institute of Genetic Medicine, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, United Kingdom.
  • McClorey G; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
  • Manzano R; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
  • Betts CA; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
  • Godfrey C; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
  • O'Donovan L; Medical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom.
  • Coursindel T; Medical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom.
  • Gait MJ; Medical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom.
  • Wood MJ; Department of Physiology Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.
  • MacGowan GA; Institute of Genetic Medicine, Newcastle University, International Centre for Life, Times Square, Newcastle upon Tyne, United Kingdom.
  • Straub VW; Department of Cardiology, Freeman Hospital, Newcastle upon Tyne, United Kingdom.
PLoS One ; 13(6): e0198897, 2018.
Article em En | MEDLINE | ID: mdl-29912990

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Distrofia Muscular de Duchenne / Peptídeos Penetradores de Células / Morfolinos / Insuficiência Cardíaca Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Distrofia Muscular de Duchenne / Peptídeos Penetradores de Células / Morfolinos / Insuficiência Cardíaca Limite: Animals Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos