Trophoblast Glycoprotein is Associated With a Favorable Outcome for Mesothelioma and a Target for Antibody Drug Conjugates.

Schunselaar, Laurel M; Monkhorst, Kim; van der Noort, Vincent; Wijdeven, Ruud; Peters, Dennis; Zwart, Wilbert; Neefjes, Jacques; Baas, Paul

Schunselaar, Laurel M; Monkhorst, Kim; van der Noort, Vincent; Wijdeven, Ruud; Peters, Dennis; Zwart, Wilbert; Neefjes, Jacques; Baas, Paul.

Afiliação

Schunselaar LM; Division of Oncogenomics, Oncode Institute within Netherlands Cancer Institute, Amsterdam, The Netherlands.
Monkhorst K; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
van der Noort V; Biometrics Department, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Wijdeven R; Department of Cell and Chemical Biology, Oncode Institute within Leiden University Medical Center, Leiden, The Netherlands.
Peters D; Core Facility Molecular Pathology & Biobanking, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Zwart W; Division of Oncogenomics, Oncode Institute within Netherlands Cancer Institute, Amsterdam, The Netherlands.
Neefjes J; Department of Cell and Chemical Biology, Oncode Institute within Leiden University Medical Center, Leiden, The Netherlands.
Baas P; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address: p.baas@nki.nl.

J Thorac Oncol ; 13(10): 1577-1587, 2018 10.

Article em En | MEDLINE | ID: mdl-29959059

Assuntos

Anticorpos Monoclonais/metabolismo; Glicoproteínas/metabolismo; Neoplasias Pulmonares/tratamento farmacológico; Mesotelioma/tratamento farmacológico; Trofoblastos/metabolismo; Humanos; Neoplasias Pulmonares/mortalidade; Neoplasias Pulmonares/patologia; Mesotelioma/mortalidade; Mesotelioma/patologia; Mesotelioma Maligno; Intervalo Livre de Progressão; Análise de Sobrevida; Resultado do Tratamento

Palavras-chave

5T4; Antibody-drug conjugate; Lysosome; Malignant pleural mesothelioma; treatment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trofoblastos / Glicoproteínas / Neoplasias Pulmonares / Mesotelioma / Anticorpos Monoclonais Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: J Thorac Oncol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda País de publicação: Estados Unidos

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