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A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes.
Meng, Weihua; Shah, Kaanan P; Pollack, Samuela; Toppila, Iiro; Hebert, Harry L; McCarthy, Mark I; Groop, Leif; Ahlqvist, Emma; Lyssenko, Valeriya; Agardh, Elisabet; Daniell, Mark; Kaidonis, Georgia; Craig, Jamie E; Mitchell, Paul; Liew, Gerald; Kifley, Annette; Wang, Jie Jin; Christiansen, Mark W; Jensen, Richard A; Penman, Alan; Hancock, Heather A; Chen, Ching J; Correa, Adolfo; Kuo, Jane Z; Li, Xiaohui; Chen, Yii-der I; Rotter, Jerome I; Klein, Ronald; Klein, Barbara; Wong, Tien Y; Morris, Andrew D; Doney, Alexander S F; Colhoun, Helen M; Price, Alkes L; Burdon, Kathryn P; Groop, Per-Henrik; Sandholm, Niina; Grassi, Michael A; Sobrin, Lucia; Palmer, Colin N A.
Afiliação
  • Meng W; Division of Population Health Sciences, Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee, Dundee, UK.
  • Shah KP; Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
  • Pollack S; Department of Epidemiology, Harvard T.H., Chan School of Public Health, Boston, Massachusetts, USA.
  • Toppila I; Folkhälsan Institute of Genetics, Folkhälsan Research Center, Helsinki, Finland.
  • Hebert HL; Abdominal Center, Nephrology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
  • McCarthy MI; Research Programs Unit, Diabetes and Obesity, University of Helsinki, Helsinki, Finland.
  • Groop L; Division of Population Health Sciences, Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee, Dundee, UK.
  • Ahlqvist E; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, Oxford, UK.
  • Lyssenko V; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Agardh E; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Headington, Oxford, UK.
  • Daniell M; Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmo, Sweden.
  • Kaidonis G; Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmo, Sweden.
  • Craig JE; Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmo, Sweden.
  • Mitchell P; Department of Clinical Sciences, Faculty of Medicine, Lund University, Malmo, Sweden.
  • Liew G; Department of Ophthalmology, Royal Melbourne Hospital, Parkville, Victoria, Australia.
  • Kifley A; Department of Ophthalmology, Flinders University, Adelaide, South Australia, Australia.
  • Wang JJ; Department of Ophthalmology, Flinders University, Adelaide, South Australia, Australia.
  • Christiansen MW; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney C24, Sydney, Australia.
  • Jensen RA; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney C24, Sydney, Australia.
  • Penman A; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney C24, Sydney, Australia.
  • Hancock HA; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney C24, Sydney, Australia.
  • Chen CJ; Cardiovascular Health Research Unit, School of Medicine, University of Washington, Seattle, Washington, USA.
  • Correa A; Cardiovascular Health Research Unit, School of Medicine, University of Washington, Seattle, Washington, USA.
  • Kuo JZ; Department of Ophthalmology, University of Mississippi Medical Center, School of Medicine, University of Mississippi, Jackson, Mississippi, USA.
  • Li X; Department of Ophthalmology, University of Mississippi Medical Center, School of Medicine, University of Mississippi, Jackson, Mississippi, USA.
  • Chen YI; Department of Ophthalmology, University of Mississippi Medical Center, School of Medicine, University of Mississippi, Jackson, Mississippi, USA.
  • Rotter JI; Department of Ophthalmology, University of Mississippi Medical Center, School of Medicine, University of Mississippi, Jackson, Mississippi, USA.
  • Klein R; Clinical and Medical Affairs, CardioDx Inc., Redwood City, California, USA.
  • Klein B; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, California, USA.
  • Wong TY; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, California, USA.
  • Morris AD; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA.
  • Doney ASF; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, California, USA.
  • Colhoun HM; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA.
  • Price AL; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, California, USA.
  • Burdon KP; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California, USA.
  • Groop PH; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
  • Sandholm N; Department of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
  • Grassi MA; Singapore Eye Research Institute, Singapore National Eye Centre, Yong Loo Lin School of Medicine, National University of Singapore, Ophthalmology and Visual Sciences Academic Clinical Program, Duke-NUS Medical School, Singapore.
  • Sobrin L; The Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.
  • Palmer CNA; Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee, Dundee, UK.
Acta Ophthalmol ; 96(7): e811-e819, 2018 Nov.
Article em En | MEDLINE | ID: mdl-30178632
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Diabetes Mellitus Tipo 2 / Retinopatia Diabética / NADPH Oxidase 4 Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Acta Ophthalmol Assunto da revista: OFTALMOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo de Nucleotídeo Único / Diabetes Mellitus Tipo 2 / Retinopatia Diabética / NADPH Oxidase 4 Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Acta Ophthalmol Assunto da revista: OFTALMOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido