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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations.
Pahuja, Kanika Bajaj; Nguyen, Thong T; Jaiswal, Bijay S; Prabhash, Kumar; Thaker, Tarjani M; Senger, Kate; Chaudhuri, Subhra; Kljavin, Noelyn M; Antony, Aju; Phalke, Sameer; Kumar, Prasanna; Mravic, Marco; Stawiski, Eric W; Vargas, Derek; Durinck, Steffen; Gupta, Ravi; Khanna-Gupta, Arati; Trabucco, Sally E; Sokol, Ethan S; Hartmaier, Ryan J; Singh, Ashish; Chougule, Anuradha; Trivedi, Vaishakhi; Dutt, Amit; Patil, Vijay; Joshi, Amit; Noronha, Vanita; Ziai, James; Banavali, Sripad D; Ramprasad, Vedam; DeGrado, William F; Bueno, Raphael; Jura, Natalia; Seshagiri, Somasekar.
Afiliação
  • Pahuja KB; Molecular Biology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Nguyen TT; Molecular Biology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Jaiswal BS; Molecular Biology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Prabhash K; Tata Memorial Hospital, Parel, Mumbai 400012, India.
  • Thaker TM; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94158, USA.
  • Senger K; Molecular Biology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Chaudhuri S; Molecular Biology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Kljavin NM; Molecular Oncology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Antony A; Department of Molecular Biology, SciGenom Labs, Cochin, Kerala 682037, India.
  • Phalke S; Research Division, MedGenome Labs Pvt. Ltd., Bangalore, Karnataka 560099, India.
  • Kumar P; Research Division, MedGenome Labs Pvt. Ltd., Bangalore, Karnataka 560099, India.
  • Mravic M; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA.
  • Stawiski EW; Molecular Biology Department, Genentech Inc., South San Francisco, CA 94080, USA; Bioinformatics and Computational Biology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Vargas D; Research and Development Department, MedGenome Inc., Foster City, CA 94404, USA.
  • Durinck S; Molecular Biology Department, Genentech Inc., South San Francisco, CA 94080, USA; Bioinformatics and Computational Biology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Gupta R; Bioinformatics Department, MeGenome Labs Pvt. Ltd., Bangalore, Karnataka 560099, India.
  • Khanna-Gupta A; Research Division, MedGenome Labs Pvt. Ltd., Bangalore, Karnataka 560099, India.
  • Trabucco SE; Foundation Medicine Inc., 150 Second Street, Cambridge, MA 02141, USA.
  • Sokol ES; Foundation Medicine Inc., 150 Second Street, Cambridge, MA 02141, USA.
  • Hartmaier RJ; Foundation Medicine Inc., 150 Second Street, Cambridge, MA 02141, USA.
  • Singh A; Department of Medical Oncology, Christian Medical College and Hospital, Vellore 632004, India.
  • Chougule A; Tata Memorial Hospital, Parel, Mumbai 400012, India.
  • Trivedi V; Tata Memorial Hospital, Parel, Mumbai 400012, India.
  • Dutt A; ACTREC, Tata Memorial Centre, Navi Mumbai 410210, India; Homi Bhaba National Institute, Training School Complex, Anushakti Nagar, Mumbai 400094, India.
  • Patil V; Tata Memorial Hospital, Parel, Mumbai 400012, India.
  • Joshi A; Tata Memorial Hospital, Parel, Mumbai 400012, India.
  • Noronha V; Tata Memorial Hospital, Parel, Mumbai 400012, India.
  • Ziai J; Pathology Department, Genentech Inc., South San Francisco, CA 94080, USA.
  • Banavali SD; Tata Memorial Hospital, Parel, Mumbai 400012, India.
  • Ramprasad V; Research Division, MedGenome Labs Pvt. Ltd., Bangalore, Karnataka 560099, India.
  • DeGrado WF; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA.
  • Bueno R; Division of Thoracic Surgery, The Lung Center and the International Mesothelioma Program, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Jura N; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA 94158, USA.
  • Seshagiri S; Molecular Biology Department, Genentech Inc., South San Francisco, CA 94080, USA. Electronic address: sekar@gene.com.
Cancer Cell ; 34(5): 792-806.e5, 2018 11 12.
Article em En | MEDLINE | ID: mdl-30449325

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor ErbB-2 / Domínios Proteicos / Neoplasias Pulmonares Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptor ErbB-2 / Domínios Proteicos / Neoplasias Pulmonares Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Cell Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos