A coronary artery disease-associated tRNAThr mutation altered mitochondrial function, apoptosis and angiogenesis.

Jia, Zidong; Zhang, Ye; Li, Qiang; Ye, Zhenzhen; Liu, Yuqi; Fu, Changzhu; Cang, Xiaohui; Wang, Meng; Guan, Min-Xin

Jia, Zidong; Zhang, Ye; Li, Qiang; Ye, Zhenzhen; Liu, Yuqi; Fu, Changzhu; Cang, Xiaohui; Wang, Meng; Guan, Min-Xin.

Afiliação

Jia Z; Division of Medical Genetics and Genomics, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Zhang Y; Institute of Genetics, Zhejiang University and Department of Human Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Li Q; Institute of Genetics, Zhejiang University and Department of Human Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Ye Z; Institute of Genetics, Zhejiang University and Department of Human Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Liu Y; Institute of Genetics, Zhejiang University and Department of Human Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Fu C; Cardiac Department, PLA General Hospital, Beijing 100853, China.
Cang X; Institute of Genetics, Zhejiang University and Department of Human Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Wang M; Division of Medical Genetics and Genomics, The Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Guan MX; Institute of Genetics, Zhejiang University and Department of Human Genetics, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.

Nucleic Acids Res ; 47(4): 2056-2074, 2019 02 28.

Article em En | MEDLINE | ID: mdl-30541130

Assuntos

Mitocôndrias/genética; Neovascularização Patológica/genética; RNA de Transferência de Treonina/química; RNA de Transferência/genética; Apoptose/genética; Doença da Artéria Coronariana/genética; Doença da Artéria Coronariana/patologia; DNA Mitocondrial/genética; Células Endoteliais da Veia Umbilical Humana; Humanos; Mitocôndrias/patologia; Mutação; Conformação de Ácido Nucleico; RNA de Transferência de Treonina/genética; Espécies Reativas de Oxigênio/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA de Transferência / RNA de Transferência de Treonina / Mitocôndrias / Neovascularização Patológica Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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