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Early Loss of Histone H2B Monoubiquitylation Alters Chromatin Accessibility and Activates Key Immune Pathways That Facilitate Progression of Ovarian Cancer.
Hooda, Jagmohan; Novak, Marián; Salomon, Matthew P; Matsuba, Chikako; Ramos, Romela I; MacDuffie, Emily; Song, Melissa; Hirsch, Michelle S; Lester, Jenny; Parkash, Vinita; Karlan, Beth Y; Oren, Moshe; Hoon, Dave S; Drapkin, Ronny.
Afiliação
  • Hooda J; Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Novak M; Department of Medical Oncology, Dana-Farber Institute, Harvard Medical School, Boston, Massachusetts.
  • Salomon MP; Department of Translational Molecular Medicine, John Wayne Cancer Institute, Providence Health Services, Santa Monica, California.
  • Matsuba C; Department of Translational Molecular Medicine, John Wayne Cancer Institute, Providence Health Services, Santa Monica, California.
  • Ramos RI; Department of Translational Molecular Medicine, John Wayne Cancer Institute, Providence Health Services, Santa Monica, California.
  • MacDuffie E; Department of Medical Oncology, Dana-Farber Institute, Harvard Medical School, Boston, Massachusetts.
  • Song M; Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Hirsch MS; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
  • Lester J; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California.
  • Parkash V; Department of Pathology, Yale University, New Haven, Connecticut.
  • Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, Los Angeles, California.
  • Oren M; Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
  • Hoon DS; Department of Translational Molecular Medicine, John Wayne Cancer Institute, Providence Health Services, Santa Monica, California.
  • Drapkin R; Penn Ovarian Cancer Research Center, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. rdrapkin@pennmedicine.upenn.edu.
Cancer Res ; 79(4): 760-772, 2019 02 15.
Article em En | MEDLINE | ID: mdl-30563893
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Cromatina / Histonas / Cistadenocarcinoma Seroso / Ubiquitina-Proteína Ligases / Neoplasias das Tubas Uterinas / Ubiquitinação Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Cromatina / Histonas / Cistadenocarcinoma Seroso / Ubiquitina-Proteína Ligases / Neoplasias das Tubas Uterinas / Ubiquitinação Tipo de estudo: Prognostic_studies Limite: Female / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos