High-throughput screening and environmental risk assessment: State of the science and emerging applications.

Villeneuve, Daniel L; Coady, Katie; Escher, Beate I; Mihaich, Ellen; Murphy, Cheryl A; Schlekat, Tamar; Garcia-Reyero, Natàlia

Villeneuve, Daniel L; Coady, Katie; Escher, Beate I; Mihaich, Ellen; Murphy, Cheryl A; Schlekat, Tamar; Garcia-Reyero, Natàlia.

Afiliação

Villeneuve DL; US Environmental Protection Agency, Mid-Continent Ecology Division, Duluth, Minnesota.
Coady K; Toxicology and Environmental Research and Consulting, The Dow Chemical Company, Midland, Michigan, USA.
Escher BI; Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.
Mihaich E; Environmental and Regulatory Resources (ER2), Durham, North Carolina, USA.
Murphy CA; Michigan State University, Fisheries and Wildlife, East Lansing, Michigan, USA.
Schlekat T; Society of Environmental Toxicology and Chemistry, Durham, North Carolina, USA.
Garcia-Reyero N; Environmental Laboratory, US Army Engineer Research and Development Center, Vicksburg, Mississippi.

Environ Toxicol Chem ; 38(1): 12-26, 2019 01.

Article em En | MEDLINE | ID: mdl-30570782

Assuntos

Ensaios de Triagem em Larga Escala/métodos; Medição de Risco; Animais; Poluentes Ambientais/análise; Humanos; Modelos Teóricos; Testes de Toxicidade

Palavras-chave

Adverse outcome pathway; Computational toxicology; Effects-based monitoring; In vitro to in vivo extrapolation; Mixtures; Risk assessment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Medição de Risco / Ensaios de Triagem em Larga Escala Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Animals / Humans Idioma: En Revista: Environ Toxicol Chem Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

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