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Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.
Nakano, Toshiaki; Katsuki, Shunsuke; Chen, Mingxian; Decano, Julius L; Halu, Arda; Lee, Lang Ho; Pestana, Diego V S; Kum, Angelo S T; Kuromoto, Rodrigo K; Golden, Whitney S; Boff, Mario S; Guimaraes, Gabriel C; Higashi, Hideyuki; Kauffman, Kevin J; Maejima, Takashi; Suzuki, Takehiro; Iwata, Hiroshi; Barabási, Albert-László; Aster, Jon C; Anderson, Daniel G; Sharma, Amitabh; Singh, Sasha A; Aikawa, Elena; Aikawa, Masanori.
Afiliação
  • Nakano T; Center for Excellence in Vascular Biology (T.N., S.K., M.C., D.V.S.P., A.S.T.K., R.K.K., W.S.G., M.S.B., G.C.G., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Katsuki S; Center for Excellence in Vascular Biology (T.N., S.K., M.C., D.V.S.P., A.S.T.K., R.K.K., W.S.G., M.S.B., G.C.G., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Chen M; Center for Excellence in Vascular Biology (T.N., S.K., M.C., D.V.S.P., A.S.T.K., R.K.K., W.S.G., M.S.B., G.C.G., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Decano JL; Center for Interdisciplinary Cardiovascular Sciences (J.L.D., A.H., L.H.L., H.H., T.M., H.I., A.S., S.A.S., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Halu A; Center for Interdisciplinary Cardiovascular Sciences (J.L.D., A.H., L.H.L., H.H., T.M., H.I., A.S., S.A.S., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Lee LH; Division of Cardiovascular Medicine, Channing Division of Network Medicine (A.H., A.-L.B., A.S., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Pestana DVS; Center for Interdisciplinary Cardiovascular Sciences (J.L.D., A.H., L.H.L., H.H., T.M., H.I., A.S., S.A.S., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Kum AST; Center for Excellence in Vascular Biology (T.N., S.K., M.C., D.V.S.P., A.S.T.K., R.K.K., W.S.G., M.S.B., G.C.G., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Kuromoto RK; Center for Excellence in Vascular Biology (T.N., S.K., M.C., D.V.S.P., A.S.T.K., R.K.K., W.S.G., M.S.B., G.C.G., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Golden WS; Center for Excellence in Vascular Biology (T.N., S.K., M.C., D.V.S.P., A.S.T.K., R.K.K., W.S.G., M.S.B., G.C.G., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Boff MS; Center for Excellence in Vascular Biology (T.N., S.K., M.C., D.V.S.P., A.S.T.K., R.K.K., W.S.G., M.S.B., G.C.G., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Guimaraes GC; Center for Excellence in Vascular Biology (T.N., S.K., M.C., D.V.S.P., A.S.T.K., R.K.K., W.S.G., M.S.B., G.C.G., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Higashi H; Center for Excellence in Vascular Biology (T.N., S.K., M.C., D.V.S.P., A.S.T.K., R.K.K., W.S.G., M.S.B., G.C.G., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Kauffman KJ; Center for Interdisciplinary Cardiovascular Sciences (J.L.D., A.H., L.H.L., H.H., T.M., H.I., A.S., S.A.S., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Maejima T; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge (K.J.K., D.G.A.).
  • Suzuki T; Center for Interdisciplinary Cardiovascular Sciences (J.L.D., A.H., L.H.L., H.H., T.M., H.I., A.S., S.A.S., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Iwata H; Division of Medical Science, Tohoku University Graduate School of Biomedical Engineering, Sendai, Japan (T.S.).
  • Barabási AL; Center for Interdisciplinary Cardiovascular Sciences (J.L.D., A.H., L.H.L., H.H., T.M., H.I., A.S., S.A.S., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Aster JC; Division of Cardiovascular Medicine, Channing Division of Network Medicine (A.H., A.-L.B., A.S., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Anderson DG; Center for Complex Network Research, Northeastern University, Boston, MA (A.-L.B.).
  • Sharma A; Department of Medicine, and Department of Pathology (J.C.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Singh SA; Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge (K.J.K., D.G.A.).
  • Aikawa E; Center for Interdisciplinary Cardiovascular Sciences (J.L.D., A.H., L.H.L., H.H., T.M., H.I., A.S., S.A.S., E.A., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  • Aikawa M; Division of Cardiovascular Medicine, Channing Division of Network Medicine (A.H., A.-L.B., A.S., M.A.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Circulation ; 139(1): 78-96, 2019 01 02.
Article em En | MEDLINE | ID: mdl-30586693
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transportadores de Ânions Orgânicos / Peptídeos e Proteínas de Sinalização Intercelular / Peptídeos e Proteínas de Sinalização Intracelular / Insuficiência Renal Crônica / Aterosclerose / Receptores Notch / Indicã / Ativação de Macrófagos / Macrófagos / Proteínas de Membrana Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Circulation Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Marrocos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transportadores de Ânions Orgânicos / Peptídeos e Proteínas de Sinalização Intercelular / Peptídeos e Proteínas de Sinalização Intracelular / Insuficiência Renal Crônica / Aterosclerose / Receptores Notch / Indicã / Ativação de Macrófagos / Macrófagos / Proteínas de Membrana Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: Circulation Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Marrocos País de publicação: Estados Unidos