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Novel PIKK inhibitor antibody-drug conjugates: Synthesis and anti-tumor activity.
Zhou, Dahui; Casavant, Jeffrey; Graziani, Edmund I; He, Haiyin; Janso, Jeffrey; Loganzo, Frank; Musto, Sylvia; Tumey, Nathan; O'Donnell, Christopher J; Dushin, Russell.
Afiliação
  • Zhou D; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, CT 06340, United States. Electronic address: dahui.zhou@pfizer.com.
  • Casavant J; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, CT 06340, United States.
  • Graziani EI; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, CT 06340, United States.
  • He H; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, CT 06340, United States.
  • Janso J; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, CT 06340, United States.
  • Loganzo F; Oncology Research East, Pfizer Worldwide Research and Development, 401 North Middletown Road, Pearl River, NY 10965, United States.
  • Musto S; Oncology Research East, Pfizer Worldwide Research and Development, 401 North Middletown Road, Pearl River, NY 10965, United States.
  • Tumey N; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, CT 06340, United States.
  • O'Donnell CJ; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, CT 06340, United States.
  • Dushin R; Oncology Medicinal Chemistry, Pfizer Worldwide Research and Development, 445 Eastern Point Road, Groton, CT 06340, United States.
Bioorg Med Chem Lett ; 29(7): 943-947, 2019 04 01.
Article em En | MEDLINE | ID: mdl-30655215
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Imunoconjugados / Trastuzumab / Inibidores de Fosfoinositídeo-3 Quinase / Aminoquinolinas / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirróis / Imunoconjugados / Trastuzumab / Inibidores de Fosfoinositídeo-3 Quinase / Aminoquinolinas / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Reino Unido