Vitamin D/VDR signaling inhibits LPS-induced IFNÎ³ and IL-1ß in Oral epithelia by regulating hypoxia-inducible factor-1&#945; signaling pathway.

Ge, Xuejun; Wang, Lixiang; Li, Mengdi; Xu, Na; Yu, Feiyan; Yang, Fang; Li, Ran; Zhang, Fang; Zhao, Bin; Du, Jie

Vitamin D/VDR signaling inhibits LPS-induced IFNÎ³ and IL-1ß in Oral epithelia by regulating hypoxia-inducible factor-1α signaling pathway.

Ge, Xuejun; Wang, Lixiang; Li, Mengdi; Xu, Na; Yu, Feiyan; Yang, Fang; Li, Ran; Zhang, Fang; Zhao, Bin; Du, Jie.

Afiliação

Ge X; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China.
Wang L; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China.
Li M; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China.
Xu N; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China.
Yu F; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China.
Yang F; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China.
Li R; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China.
Zhang F; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China.
Zhao B; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China.
Du J; Department of Oral Medicine, Shanxi Medical University School and Hospital of Stomatology, NO. 56 Xinjian South Road, Taiyuan, 030001, Shanxi, China. dj1243@hotmail.com.

Cell Commun Signal ; 17(1): 18, 2019 02 27.

Article em En | MEDLINE | ID: mdl-30813930

Assuntos

Epitélio/metabolismo; Subunidade alfa do Fator 1 Induzível por Hipóxia/metabolismo; Interferon gama/metabolismo; Interleucina-1beta/metabolismo; Lipopolissacarídeos/farmacologia; Receptores de Calcitriol/metabolismo; Transdução de Sinais; Vitamina D/metabolismo; Animais; Sequência de Bases; Calcitriol/farmacologia; Linhagem Celular; Epitélio/efeitos dos fármacos; Humanos; Subunidade alfa do Fator 1 Induzível por Hipóxia/genética; Queratinócitos/efeitos dos fármacos; Queratinócitos/metabolismo; Líquen Plano Bucal/metabolismo; Masculino; Camundongos Endogâmicos C57BL; Boca/metabolismo; NF-kappa B/metabolismo; Regulação para Cima/efeitos dos fármacos; Proteína Supressora de Tumor Von Hippel-Lindau/metabolismo

Palavras-chave

Cytokines; HIF-1α; Oral lichen planus; Vitamin D; Vitamin D receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vitamina D / Transdução de Sinais / Lipopolissacarídeos / Interferon gama / Receptores de Calcitriol / Epitélio / Subunidade alfa do Fator 1 Induzível por Hipóxia / Interleucina-1beta Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Cell Commun Signal Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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