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Amyloid ß oligomers suppress excitatory transmitter release via presynaptic depletion of phosphatidylinositol-4,5-bisphosphate.
He, Yang; Wei, Mengdi; Wu, Yan; Qin, Huaping; Li, Weinan; Ma, Xiaolin; Cheng, Jingjing; Ren, Jinshuai; Shen, Ye; Chen, Zhong; Sun, Binggui; Huang, Fu-De; Shen, Yi; Zhou, Yu-Dong.
Afiliação
  • He Y; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Wei M; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Wu Y; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Qin H; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Li W; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Ma X; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Cheng J; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Ren J; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Shen Y; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Chen Z; Department of Pharmacology, NHC and CAMS Key Laboratory of Medical Neurobiology, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, 310058, China.
  • Sun B; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China.
  • Huang FD; Center for Stem Cell and NanoMedicine, Laboratory for System Biology, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201210, China. huangfd@sari.ac.cn.
  • Shen Y; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China. yshen2@zju.edu.cn.
  • Zhou YD; Department of Neurobiology, and Department of Ophthalmology of the First Affiliated Hospital, NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University School of Medicine, Hangzhou, 310058, China. yudongzhou@zju.edu.cn.
Nat Commun ; 10(1): 1193, 2019 03 13.
Article em En | MEDLINE | ID: mdl-30867420

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Sinapses / Peptídeos beta-Amiloides / Fosfatidilinositol 4,5-Difosfato / Região CA1 Hipocampal / Doença de Alzheimer Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Sinapses / Peptídeos beta-Amiloides / Fosfatidilinositol 4,5-Difosfato / Região CA1 Hipocampal / Doença de Alzheimer Limite: Animals / Humans / Male Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido