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Design, synthesis and bioevaluation of 3-oxo-6-aryl-2,3-dihydropyridazine-4-carbohydrazide derivatives as novel xanthine oxidase inhibitors.
Zhang, Lichao; Wang, Sibo; Yang, Mingzheng; Shi, Ailong; Wang, He; Guan, Qi; Bao, Kai; Zhang, Weige.
Afiliação
  • Zhang L; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Wang S; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Yang M; School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Shi A; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Wang H; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.
  • Guan Q; School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: guanqi@syphu.edu.cn.
  • Bao K; Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: baokai@syphu.edu.cn.
  • Zhang W; Key Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China. Electronic address: zhangweige2000@sina.com.
Bioorg Med Chem ; 27(9): 1818-1823, 2019 05 01.
Article em En | MEDLINE | ID: mdl-30885567
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xantina Oxidase / Desenho de Fármacos / Inibidores Enzimáticos / Hidrazinas Limite: Animals Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Xantina Oxidase / Desenho de Fármacos / Inibidores Enzimáticos / Hidrazinas Limite: Animals Idioma: En Revista: Bioorg Med Chem Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido