Asymmetric expression of GPR126 in the convex/concave side of the spine is associated with spinal skeletal malformation in adolescent idiopathic scoliosis population.

Xu, Enjie; Lin, Tao; Jiang, Heng; Ji, Zhe; Shao, Wei; Meng, Yichen; Gao, Rui; Zhou, Xuhui

Xu, Enjie; Lin, Tao; Jiang, Heng; Ji, Zhe; Shao, Wei; Meng, Yichen; Gao, Rui; Zhou, Xuhui.

Afiliação

Xu E; Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, No. 415 Fengyang Road, Shanghai, People's Republic of China.
Lin T; Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, No. 415 Fengyang Road, Shanghai, People's Republic of China.
Jiang H; Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, No. 415 Fengyang Road, Shanghai, People's Republic of China.
Ji Z; Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, No. 415 Fengyang Road, Shanghai, People's Republic of China.
Shao W; Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, No. 415 Fengyang Road, Shanghai, People's Republic of China.
Meng Y; Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, No. 415 Fengyang Road, Shanghai, People's Republic of China.
Gao R; Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, No. 415 Fengyang Road, Shanghai, People's Republic of China. rgaospine@163.com.
Zhou X; Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, No. 415 Fengyang Road, Shanghai, People's Republic of China. xhzhouspine@163.com.

Eur Spine J ; 28(9): 1977-1986, 2019 Sep.

Article em En | MEDLINE | ID: mdl-31079250

Assuntos

Anormalidades Musculoesqueléticas/metabolismo; Receptores Acoplados a Proteínas G/biossíntese; Escoliose/metabolismo; Adolescente; Diferenciação Celular/fisiologia; Células Cultivadas; Criança; Feminino; Regulação da Expressão Gênica/fisiologia; Técnicas de Silenciamento de Genes; Humanos; Masculino; Células-Tronco Mesenquimais/metabolismo; Células-Tronco Mesenquimais/patologia; Anormalidades Musculoesqueléticas/genética; Anormalidades Musculoesqueléticas/patologia; Osteogênese/genética; Osteogênese/fisiologia; Receptores Acoplados a Proteínas G/genética; Receptores Acoplados a Proteínas G/fisiologia; Escoliose/genética; Escoliose/patologia; Escoliose/cirurgia; Coluna Vertebral/patologia; Coluna Vertebral/fisiopatologia

Palavras-chave

Adolescent idiopathic scoliosis; Bone formation; GPR126; N-terminal fragment; Transcript

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Escoliose / Receptores Acoplados a Proteínas G / Anormalidades Musculoesqueléticas Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Eur Spine J Assunto da revista: ORTOPEDIA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Alemanha

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