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Synthesis and biological evaluation of 5-aminoethyl benzophenanthridone derivatives as DNA topoisomerase IB inhibitors.
Tang, Wen-Lin; Zhang, Yu; Hu, De-Xuan; Yang, Hui; Yu, Qian; Chen, Jian-Wen; Agama, Keli; Pommier, Yves; An, Lin-Kun.
Afiliação
  • Tang WL; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, 510006, China.
  • Zhang Y; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Hu DX; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Yang H; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Yu Q; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Chen JW; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China.
  • Agama K; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • Pommier Y; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.
  • An LK; School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, China; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangzhou, 510006, China. Electronic address: lssalk@mail.sysu.edu.cn.
Eur J Med Chem ; 178: 81-92, 2019 Sep 15.
Article em En | MEDLINE | ID: mdl-31176097
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzofenantridinas / Inibidores da Topoisomerase I / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: França
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzofenantridinas / Inibidores da Topoisomerase I / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: França