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Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation.
Bailey, Jade D; Diotallevi, Marina; Nicol, Thomas; McNeill, Eileen; Shaw, Andrew; Chuaiphichai, Surawee; Hale, Ashley; Starr, Anna; Nandi, Manasi; Stylianou, Elena; McShane, Helen; Davis, Simon; Fischer, Roman; Kessler, Benedikt M; McCullagh, James; Channon, Keith M; Crabtree, Mark J.
Afiliação
  • Bailey JD; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.
  • Diotallevi M; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.
  • Nicol T; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.
  • McNeill E; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.
  • Shaw A; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.
  • Chuaiphichai S; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.
  • Hale A; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.
  • Starr A; School of Cancer and Pharmaceutical Science, Faculty of Life Sciences and Medicine, King's College London, London SE1 9NH, UK.
  • Nandi M; School of Cancer and Pharmaceutical Science, Faculty of Life Sciences and Medicine, King's College London, London SE1 9NH, UK.
  • Stylianou E; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.
  • McShane H; Jenner Institute, University of Oxford, Oxford OX3 7DQ, UK.
  • Davis S; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK.
  • Fischer R; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK.
  • Kessler BM; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7FZ, UK.
  • McCullagh J; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, UK.
  • Channon KM; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK. Electronic address: keith.channon@cardiov.ox.ac.uk.
  • Crabtree MJ; BHF Centre of Research Excellence, Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK. Electronic address: mark.crabtree@well.ox.ac.uk.
Cell Rep ; 28(1): 218-230.e7, 2019 07 02.
Article em En | MEDLINE | ID: mdl-31269442
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Succinatos / Ciclo do Ácido Cítrico / Inflamação / Macrófagos / Óxido Nítrico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Succinatos / Ciclo do Ácido Cítrico / Inflamação / Macrófagos / Óxido Nítrico Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos