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Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
Ma, Jun; Zhao, Shoujing; Qiao, Xinan; Knight, Tristan; Edwards, Holly; Polin, Lisa; Kushner, Juiwanna; Dzinic, Sijana H; White, Kathryn; Wang, Guan; Zhao, Lijing; Lin, Hai; Wang, Yue; Taub, Jeffrey W; Ge, Yubin.
Afiliação
  • Ma J; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, China.
  • Zhao S; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, China.
  • Qiao X; National Engineering Laboratory for AIDS Vaccine, School of Life Sciences, Jilin University, Changchun, China.
  • Knight T; Division of Pediatric Hematology and Oncology, Department of Pediatrics, Children's Hospital of Michigan, Detroit, Michigan.
  • Edwards H; Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan.
  • Polin L; Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan.
  • Kushner J; Molecular Therapeutics Program, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan.
  • Dzinic SH; Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan.
  • White K; Molecular Therapeutics Program, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan.
  • Wang G; Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan.
  • Zhao L; Molecular Therapeutics Program, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan.
  • Lin H; Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan.
  • Wang Y; Molecular Therapeutics Program, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan.
  • Taub JW; Department of Oncology, Wayne State University School of Medicine, Detroit, Michigan.
  • Ge Y; Molecular Therapeutics Program, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan.
Clin Cancer Res ; 25(22): 6815-6826, 2019 11 15.
Article em En | MEDLINE | ID: mdl-31320594
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazinas / Leucemia Mieloide Aguda / Estaurosporina / Proteínas Proto-Oncogênicas c-bcl-2 / Inibidores de Proteínas Quinases / Tirosina Quinase 3 Semelhante a fms / Compostos de Anilina / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazinas / Leucemia Mieloide Aguda / Estaurosporina / Proteínas Proto-Oncogênicas c-bcl-2 / Inibidores de Proteínas Quinases / Tirosina Quinase 3 Semelhante a fms / Compostos de Anilina / Mutação Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos