CYP1A1 methylation mediates the effect of smoking and occupational polycyclic aromatic hydrocarbons co-exposure on oxidative DNA damage among Chinese coke-oven workers.

Liu, Yanli; Li, Xuejing; Zhang, Bin; Fu, Ye; Yang, Aimin; Zhang, Hongjie; Zhang, Huitao; Niu, Yingying; Nie, Jisheng; Yang, Jin

Liu, Yanli; Li, Xuejing; Zhang, Bin; Fu, Ye; Yang, Aimin; Zhang, Hongjie; Zhang, Huitao; Niu, Yingying; Nie, Jisheng; Yang, Jin.

Afiliação

Liu Y; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Xinjiannan Road 56, Taiyuan, 030001, Shanxi, China.
Li X; Department of Preventive Medicine, School of Public Health and Management, Hubei University of Medicine, Shiyan, Hubei, China.
Zhang B; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Xinjiannan Road 56, Taiyuan, 030001, Shanxi, China.
Fu Y; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Xinjiannan Road 56, Taiyuan, 030001, Shanxi, China.
Yang A; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Xinjiannan Road 56, Taiyuan, 030001, Shanxi, China.
Zhang H; Hong Kong Institute of Diabetes and Obesity, the Chinese University of Hong Kong, Hong Kong SAR, People's Republic of China.
Zhang H; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Xinjiannan Road 56, Taiyuan, 030001, Shanxi, China.
Niu Y; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Xinjiannan Road 56, Taiyuan, 030001, Shanxi, China.
Nie J; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Xinjiannan Road 56, Taiyuan, 030001, Shanxi, China.
Yang J; Department of Occupational Health, School of Public Health, Shanxi Medical University, Taiyuan, Xinjiannan Road 56, Taiyuan, 030001, Shanxi, China.

Environ Health ; 18(1): 69, 2019 07 29.

Article em En | MEDLINE | ID: mdl-31358014

Assuntos

Citocromo P-450 CYP1A1/genética; Dano ao DNA; Metilação de DNA; Exposição Ocupacional/análise; Hidrocarbonetos Policíclicos Aromáticos/efeitos adversos; Fumar/efeitos adversos; Adulto; China; Estudos Transversais; Citocromo P-450 CYP1A1/metabolismo; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Estresse Oxidativo

Palavras-chave

Cytochrome P4501A1; DNA methylation; Oxidative DNA damage; Polycyclic aromatic hydrocarbons; Smoking

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hidrocarbonetos Policíclicos Aromáticos / Dano ao DNA / Fumar / Exposição Ocupacional / Citocromo P-450 CYP1A1 / Metilação de DNA Tipo de estudo: Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged País/Região como assunto: Asia Idioma: En Revista: Environ Health Assunto da revista: SAUDE AMBIENTAL Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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