Growth-coupled evolution of phosphoketolase to improve L-glutamate production by Corynebacterium glutamicum.

Dele-Osibanjo, Taiwo; Li, Qinggang; Zhang, Xiaoli; Guo, Xuan; Feng, Jinhui; Liu, Jiao; Sun, Xue; Wang, Xiaowei; Zhou, Wenjuan; Zheng, Ping; Sun, Jibin; Ma, Yanhe

Dele-Osibanjo, Taiwo; Li, Qinggang; Zhang, Xiaoli; Guo, Xuan; Feng, Jinhui; Liu, Jiao; Sun, Xue; Wang, Xiaowei; Zhou, Wenjuan; Zheng, Ping; Sun, Jibin; Ma, Yanhe.

Afiliação

Dele-Osibanjo T; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Li Q; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Zhang X; University of Chinese Academy of Sciences, Beijing, 100049, China.
Guo X; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Feng J; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Liu J; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Sun X; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Wang X; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Zhou W; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Zheng P; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Sun J; Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Ma Y; Key Laboratory of Systems Microbial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.

Appl Microbiol Biotechnol ; 103(20): 8413-8425, 2019 Oct.

Article em En | MEDLINE | ID: mdl-31399771

Assuntos

Aldeído Liases/metabolismo; Corynebacterium glutamicum/enzimologia; Corynebacterium glutamicum/crescimento & desenvolvimento; Ácido Glutâmico/metabolismo; Mutação; Proteínas Recombinantes/metabolismo; Aldeído Liases/genética; Bifidobacterium adolescentis/enzimologia; Bifidobacterium adolescentis/genética; Corynebacterium glutamicum/genética; Corynebacterium glutamicum/metabolismo; Evolução Molecular Direcionada; Cinética; Mutagênese Sítio-Dirigida; Proteínas Recombinantes/genética; Seleção Genética

Palavras-chave

Acetyl CoA generation; Corynebacterium glutamicum; Growth-coupled evolution; L-glutamate production; Phosphoketolase

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes / Ácido Glutâmico / Corynebacterium glutamicum / Aldeído Liases / Mutação Idioma: En Revista: Appl Microbiol Biotechnol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Alemanha

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