A rare case of Ganglioneuroblastoma Encapsulated in Pheochromocytoma

ABSTRACT

Pheochromocytoma and Ganglioneuroblastoma are separate diseases and a rare combination in which the diagnosis can only be confirmed by pathological examination after tumor excision. We reported here a case of ganglioneuroblastomaencapsulated in pheochromocytoma. The patient is a woman, 73 years old, hypertensive, with hypothyroidism,associated for 15 years with hypercholesterolemia and hypertriglyceridemia, which had frequent complaints of low backpain. She underwent magnetic resonance and the findings were consistent with the diagnosis of pheochromocytoma. Aftersurgery, anatomic, pathologic and immunohistochemistry analysis confirmed the diagnosis of pheochromocytoma composedby small ganglioneuroblastoma representation with the identification of small focus of infiltration of the adrenal capsule and adipose tissue by pheochromocytoma. This rare association can instigate the discussion of methods of diagnosis, moreeffective and more appropriate treatments for each patient...