Detalhe da pesquisa
1.
Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis.
Nat Chem Biol;
20(2): 243-250, 2024 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37945897
2.
A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products.
Proc Natl Acad Sci U S A;
120(9): e2220468120, 2023 02 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36802426
3.
MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters.
Nucleic Acids Res;
51(D1): D603-D610, 2023 01 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36399496
4.
Discrete Acyltransferases and Thioesterases in Iso-Migrastatin and Lactimidomycin Biosynthesis.
Biochemistry;
2024 Feb 12.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38345531
5.
Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization.
J Ind Microbiol Biotechnol;
512024 Jan 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38262768
6.
Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis.
J Am Chem Soc;
144(44): 20452-20462, 2022 11 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36279548
7.
Cryptic Sulfur Incorporation in Thioangucycline Biosynthesis.
Angew Chem Int Ed Engl;
60(13): 7140-7147, 2021 03 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33465268
8.
Engineering the Substrate Specificity of a Modular Polyketide Synthase for Installation of Consecutive Non-Natural Extender Units.
J Am Chem Soc;
141(5): 1961-1969, 2019 02 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30676722
9.
Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis.
J Am Chem Soc;
141(9): 4043-4050, 2019 03 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30735041
10.
Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis.
J Am Chem Soc;
141(31): 12406-12412, 2019 08 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31291107
11.
The Natural Products Discovery Center: Release of the First 8490 Sequenced Strains for Exploring Actinobacteria Biosynthetic Diversity.
bioRxiv;
2024 May 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38168313
12.
Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase.
Nat Commun;
12(1): 2193, 2021 04 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33850151
13.
Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase.
Nat Commun;
12(1): 5672, 2021 09 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34584078
14.
PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine N-Acetyltransferases.
ACS Chem Biol;
16(1): 96-105, 2021 01 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33314918
15.
Targeting Bacterial Genomes for Natural Product Discovery.
Trends Pharmacol Sci;
41(1): 13-26, 2020 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31822352
16.
Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli.
ACS Synth Biol;
8(6): 1391-1400, 2019 06 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31134799
17.
Engineering enzymatic assembly lines for the production of new antimicrobials.
Curr Opin Microbiol;
45: 140-148, 2018 10.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29733997
18.
MIO-containing aminomutases for α- to ß-amino acids.
Trends Chem;
4(1): 91-92, 2022 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36304426
19.
Stem cell patents--reexamination/litigation--the last 5 years.
Tissue Eng Part B Rev;
15(1): 87-90, 2009 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19260807