Detalhe da pesquisa
1.
Main-chain Macromolecular Hydrazone Photoswitches.
Angew Chem Int Ed Engl;
63(4): e202315887, 2024 Jan 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37988197
2.
The efficacy of the analgesic GlyT2 inhibitor, ORG25543, is determined by two connected allosteric sites.
J Neurochem;
2023 Dec 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38131125
3.
Visible-Light-Reactive Single-Chain Nanoparticles.
Angew Chem Int Ed Engl;
62(23): e202302995, 2023 Jun 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36882373
4.
The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity.
J Biol Chem;
296: 100282, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33450225
5.
Hydroxy Groups Enhance [2]Rotaxane Anion Binding Selectivity.
Chemistry;
28(28): e202200389, 2022 May 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-35293643
6.
Protonophoric and mitochondrial uncoupling activity of aryl-carbamate substituted fatty acids.
Org Biomol Chem;
21(1): 132-139, 2022 12 21.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36453203
7.
High resolution crystal structure of a KRAS promoter G-quadruplex reveals a dimer with extensive poly-A π-stacking interactions for small-molecule recognition.
Nucleic Acids Res;
48(10): 5766-5776, 2020 06 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32313953
8.
The role of plasmalogens, Forssman lipids, and sphingolipid hydroxylation in modulating the biophysical properties of the epithelial plasma membrane.
J Chem Phys;
154(9): 095101, 2021 Mar 07.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33685172
9.
Understanding the Link between Lipid Diversity and the Biophysical Properties of the Neuronal Plasma Membrane.
Biochemistry;
59(33): 3010-3018, 2020 08 25.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32786397
10.
Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane.
J Struct Biol;
211(1): 107513, 2020 07 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-32339763
11.
Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding.
Proc Natl Acad Sci U S A;
114(9): 2218-2223, 2017 02 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28193899
12.
Probing the Pharmacological Binding Sites of P-Glycoprotein Using Umbrella Sampling Simulations.
J Chem Inf Model;
59(5): 2287-2298, 2019 05 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30540465
13.
A potential new, stable state of the E-cadherin strand-swapped dimer in solution.
Eur Biophys J;
47(1): 59-67, 2018 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28620741
14.
Understanding the accumulation of P-glycoprotein substrates within cells: The effect of cholesterol on membrane partitioning.
Biochim Biophys Acta;
1858(4): 776-82, 2016 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26724201
15.
Hydrophobic Shielding Drives Catalysis of Hydride Transfer in a Family of F420H2-Dependent Enzymes.
Biochemistry;
55(49): 6908-6918, 2016 Dec 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27951661
16.
Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin.
J Biol Chem;
290(40): 24308-25, 2015 Oct 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26240152
17.
Imperfect coordination chemistry facilitates metal ion release in the Psa permease.
Nat Chem Biol;
10(1): 35-41, 2014 Jan.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24212134
18.
AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae.
Mol Microbiol;
91(4): 834-51, 2014 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24428621
19.
Identification of Possible Binding Sites for Morphine and Nicardipine on the Multidrug Transporter P-Glycoprotein Using Umbrella Sampling Techniques.
J Chem Inf Model;
55(6): 1202-17, 2015 Jun 22.
Artigo
em Inglês
| MEDLINE
| ID: mdl-25938863
20.
ABC transporters: a riddle wrapped in a mystery inside an enigma.
Trends Biochem Sci;
34(10): 520-31, 2009 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19748784