RESUMEN
Tropical cyclones (TCs) pose a significant threat to human health, and research is needed to identify high-risk subpopulations. We investigated whether hospitalization risks from TCs in Florida (FL), United States, varied across individuals and communities. We modeled the associations between all storms in FL from 1999 to 2016 and over 3.5 million Medicare hospitalizations for respiratory (RD) and cardiovascular disease (CVD). We estimated the relative risk (RR), comparing hospitalizations during TC-periods (2 days before to 7 days after) to matched non-TC-periods. We then separately modeled the associations in relation to individual and community characteristics. TCs were associated with elevated risk of RD hospitalizations (RR: 4.37, 95% CI: 3.08, 6.19), but not CVD (RR: 1.04, 95% CI: 0.87, 1.24). There was limited evidence of modification by individual characteristics (age, sex, or Medicaid eligibility); however, risks were elevated in communities with higher poverty or lower homeownership (for CVD hospitalizations) and in denser or more urban communities (for RD hospitalizations). More research is needed to understand the potential mechanisms and causal pathways that might account for the observed differences in the association between tropical cyclones and hospitalizations across communities.
Asunto(s)
Enfermedades Cardiovasculares , Tormentas Ciclónicas , Humanos , Estados Unidos , Anciano , Florida/epidemiología , Medicare , Factores de Riesgo , Enfermedades Cardiovasculares/epidemiologíaRESUMEN
A new method of color moiré fringe simulation in the contact-type 3-D displays is introduced. The method allows simulating color moirés appearing in the displays, which cannot be approximated by conventional cosine approximation of a line grating. The color moirés are mainly introduced by the line width of the boundary lines between the elemental optics in and plate thickness of viewing zone forming optics. This is because the lines are hiding some parts of pixels under the viewing zone forming optics, and the plate thickness induces a virtual contraction of the pixels. The simulated color moiré fringes are closely matched with those appearing at the displays.
Asunto(s)
Simulación por Computador , Imagenología Tridimensional , ColorRESUMEN
Epitaxial films of Li2MnO3 were synthesized using pulsed laser deposition. A 12.6 nm film exhibited a high discharge capacity of over 300 mA h g(-1) following its fiftieth cycle and better stability than 29.8 and 47.8 nm films. The surfaces of such films are intrinsically active at the electrochemical interface.
RESUMEN
Primary tumors of the great vessels are very rare. Primary leiomyosarcomas of the pulmonary vein are extremely rare and little is known about their clinical manifestation and treatment. We report the case of a 34-year-old patient with primary leiomyosarcoma of the pulmonary vein extending into the left atrium. A review of the clinical manifestation and treatment of 24 cases including our own is provided.
Asunto(s)
Atrios Cardíacos/patología , Leiomiosarcoma/diagnóstico , Leiomiosarcoma/patología , Venas Pulmonares/patología , Neoplasias Vasculares/diagnóstico , Neoplasias Vasculares/patología , Adulto , Ecocardiografía Transesofágica , Femenino , Atrios Cardíacos/cirugía , Humanos , Interpretación de Imagen Asistida por Computador , Leiomiosarcoma/cirugía , Imagen por Resonancia Magnética , Imagen Multimodal , Invasividad Neoplásica , Tomografía de Emisión de Positrones , Venas Pulmonares/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Neoplasias Vasculares/cirugíaRESUMEN
Klinefelter's syndrome, which is characterized by small testes, gynecomastia, hypogonadism, and infertility, is the most common cause of primary testicular failure, and commonly has an XXY karyotype. Deep vein thrombosis and thomboembolic events are a rare occurrence in these patients. Although the exact mechanism is not completely understood, it is thought that increased thromboembolic risk in hypogonadic men can be explained by hypofibrinolysis resulting from androgen deficiency. We present the case of a 48-year-old man with Klinefelter's syndrome who experienced recurrent episodes of deep venous thrombosis and pulmonary embolism while undergoing therapeutic anticoagulation. Our report discusses this association and management of the prothrombotic state in patients with Klinefelter's syndrome.
Asunto(s)
Fibrinolíticos/uso terapéutico , Síndrome de Klinefelter/diagnóstico , Síndrome de Klinefelter/terapia , Embolia Pulmonar/diagnóstico , Embolia Pulmonar/prevención & control , Trombosis de la Vena/diagnóstico , Trombosis de la Vena/prevención & control , Humanos , Masculino , Persona de Mediana Edad , Recurrencia , Resultado del TratamientoRESUMEN
BACKGROUND: Previous studies identified clinical and physiologic factors of idiopathic pulmonary fibrosis (IPF) that are related to an increased risk of mortality. But there are few studies about histologic and molecular approach. OBJECTIVE: We investigated whether the C-reactive protein (CRP), fibroblastic foci, phosphorylated Smad2/3 (p-Smad2/3), tumor growth factor-beta (TGF-beta), TGF-beta receptor II (TbetaRII), and the polymorphism of the TGF-beta1 codon 10 are associated with the progression of IPF patients. DESIGN: Eighty-six IPF patients who underwent surgical lung biopsies were examined. For each patient, clinical and physiologic parameters were investigated, and we performed immunohistochemical staining for p-Smad2/3 and TbetaRII, and genotyping of the TGF-beta1 codon 10 polymorphism. RESULTS: Age at diagnosis, gender, symptom duration, and smoking status did not show a significant association. However, the amount of smoking (p = 0.002), severe reduction in the percentages of predicted forced vital capacity (p = 0.013) and diffusion lung capacity of carbon monoxide (p = 0.023), CRP (p = 0.009) at diagnosis, and fibroblastic foci (p = 0.026) were associated with a poor prognosis. Cellularity, fibrosis, expression level of p-Smad2/3 and TbetaRII, and genotype of the TGF-beta1 codon 10 polymorphism did not have a statistically significant association with the prognosis. CONCLUSION: This study confirmed the amount of smoking, abrupt decrease in follow-up pulmonary function parameters, fibroblastic foci, and increased levels of CRP concentration at diagnosis were significantly associated with poor survival. Larger studies are required to confirm all prognostic factors including CRP.
Asunto(s)
Fibrosis Pulmonar Idiopática/diagnóstico , Pulmón , Anciano , Biomarcadores/análisis , Biopsia , Proteína C-Reactiva/análisis , Codón , Femenino , Fibroblastos/patología , Volumen Espiratorio Forzado , Humanos , Fibrosis Pulmonar Idiopática/genética , Fibrosis Pulmonar Idiopática/metabolismo , Fibrosis Pulmonar Idiopática/mortalidad , Fibrosis Pulmonar Idiopática/patología , Fibrosis Pulmonar Idiopática/fisiopatología , Inmunohistoquímica , Estimación de Kaplan-Meier , Pulmón/química , Pulmón/patología , Pulmón/fisiopatología , Masculino , Persona de Mediana Edad , Fosforilación , Reacción en Cadena de la Polimerasa , Polimorfismo Genético , Pronóstico , Modelos de Riesgos Proporcionales , Proteínas Serina-Treonina Quinasas/análisis , Receptor Tipo II de Factor de Crecimiento Transformador beta , Receptores de Factores de Crecimiento Transformadores beta/análisis , República de Corea , Medición de Riesgo , Factores de Riesgo , Proteína Smad2/análisis , Proteína smad3/análisis , Fumar/efectos adversos , Factor de Crecimiento Transformador beta1/análisis , Factor de Crecimiento Transformador beta1/genética , Capacidad VitalRESUMEN
We demonstrated the writing and reading of conducting nanobits on a NiO thin film deposited on Pt/TiO(2)/SiO(2)/Si substrates for a resistive random access memory (RRAM) application using conducting atomic force microscopy (CAFM) and Kelvin probe force microscopy (KFM). A Pt/NiO/Pt RRAM capacitor showed a typical unipolar switching behavior with bistable resistances. Conducting nanobits with diameters of 22 nm written with a bias of 3.0 V on the NiO thin film were observed with CAFM. The conducting nanobits observed by KFM exhibited negative potentials relative to the insulating regions when there was no bias at the Pt bottom electrode because image charges were induced by charges formed at the end of the KFM tip by the reference AC bias. Enhancement of the KFM signals for conducting nanobits was achieved using specific biases at the Pt bottom electrode, which provided clear KFM images for conducting nanobits.
RESUMEN
OBJECTIVES: To investigate the anti-fatigue effects of Myelophil, an extract of a mix of Astragali Radix and Salviae Radix, which has been used to treat patients with chronic fatigue. SUBJECTS AND DESIGN: A randomised, double-blind, controlled clinical trial was performed with 36 adults who complained of chronic fatigue. The subjects were divided among a control group and low- and high-dose groups (3 or 6g of oral Myelophil per day, respectively) and were monitored for 4 weeks. Fatigue severity was subjectively characterised, and the expression of 42 cytokines was evaluated using an antibody array. RESULTS: Myelophil administration (3g per day) significantly decreased the fatigue severity score compared with the control (p<0.05). No changes were noted in cytokine expression. CONCLUSIONS: Myelophil appears to have a pharmacological effect against fatigue, suggesting the clinical relevance of the traditional medicinal plants, Astragalus membranaceus and Salvia miltiorrhiza.
Asunto(s)
Astragalus propinquus , Medicamentos Herbarios Chinos/uso terapéutico , Síndrome de Fatiga Crónica/tratamiento farmacológico , Fitoterapia , Extractos Vegetales/uso terapéutico , Salvia miltiorrhiza , Adulto , Citocinas/sangre , Citocinas/inmunología , Método Doble Ciego , Medicamentos Herbarios Chinos/farmacología , Síndrome de Fatiga Crónica/clasificación , Síndrome de Fatiga Crónica/inmunología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Extractos Vegetales/inmunología , Extractos Vegetales/farmacología , Raíces de Plantas , Plantas Medicinales , Índice de Severidad de la Enfermedad , Adulto JovenRESUMEN
We have studied the electronic structure of the Ni triangular lattice in NiGa(2)S(4) using photoemission spectroscopy and subsequent model calculations. The cluster-model analysis of the Ni 2p core-level spectrum shows that the S 3p to Ni 3d charge-transfer energy is approximately -1 eV and the ground state is dominated by the d(9)L configuration (L is a S 3p hole). Cell perturbation analysis for the NiS(2) triangular lattice indicates that the strong S 3p hole character of the ground state provides the enhanced superexchange interaction between the third-nearest-neighbor sites.
RESUMEN
X-ray photoemission spectroscopy measurements were performed on thin-film samples of rutile Ti(1-x)Co(x)O(2-delta) to reveal the electronic structure. The Co 2p core-level spectra indicate that the Co ions take the high-spin Co2+ configuration, consistent with substitution on the Ti site. The high-spin state and the shift due to the exchange splitting of the conduction band suggest strong hybridization between carriers in the Ti 3d t(2g) band and the t(2g) states of the high-spin Co+2 . These observations support the argument that room temperature ferromagnetism in Ti(1-x)Co(x)O(2-delta) is intrinsic.
RESUMEN
We have studied the electronic structure of the spinel-type compound CuIr2S4 using x-ray photoemission spectroscopy (XPS). CuIr2S4 undergoes a metal-insulator transition (MIT) at approximately 226 K. In going from the metallic to insulating states, the valence-band photoemission spectrum shows a gap opening at the Fermi level and a rigid-band shift of approximately 0.15 eV. In addition, the Ir 4f core-level spectrum is dramatically changed by the MIT. The Ir 4f line shape of the insulating state can be decomposed into two contributions, consistent with the charge disproportionation of Ir3+:Ir4+=1:1. XPS measurements under laser irradiation indicate that the charge disproportionation of CuIr2S4 is very robust against photo-excitation in contrast to Cs2Au2Br6 which shows photo-induced valence transition.
RESUMEN
A multichannel acousto-optic Bragg cell was made by the joining of acousto-optic cells that have the shape of symmetrical trapezoidal prisms. This acousto-optic Bragg cell has an aperture length equal to the sum of its component acousto-optic cells but has an aperture time equal to that of each acousto-optic cell. We tested the performance of the multichannel acousto-optic Bragg cell by joining six TeO(2) acousto-optic cells together with 300-microm gaps between one another. The holographic fringe data prepared by computer were divided into six equal segments. Each data segment was again divided into six equal parts and then fed into the corresponding acousto-optic cell. The holographic images were reconstructed by the periodical illumination of a green (lambda = 0.5145 microm) pulse laser beam onto the multichannel acousto-optic Bragg cell. The reconstructed images are sharp and clear. This indicates that the multichannel acousto-optic Bragg cell is working properly.
RESUMEN
A highly diverging laser beam is used to measure angular and spectral selectivities and grating vector direction for reflection-type holographic optical elements (HOE's). The intensity distribution of the beam transmitted from the HOE's reveals dark, ring-shaped patterns. Since these ring patterns are formed as a result of the beam diffracted by the HOE's, the thicknesses and the diameters of the ring patterns convey information on both the angular and the spectral selectivities of the HOE's. In addition the deviation of the ring centers relative to the center of the intensity distribution reveals the grating vector direction. Determination of values related to the ring patterns permits highly accurate measurement of HOE characteristics, such as the upper limit of the diffraction wavelength, the angular and the spectral selectivities, and the grating vector direction. This is proved experimentally.
RESUMEN
The main drawback of the use of transmission-type holographic screens is poor color reproduction caused by their high spectral dispersion. For overcoming this drawback, a long, narrow diffusing slit is used as an object when recording the screen. The necessary size and position of the slit relative to the photoplate and to the recording and reconstruction beams are determined by the phase relations of the beams. By use of the slit, holographic screens of 30 cm x 40 cm are recorded with a diverging reference beam and are used to display a multiview full-color stereoscopic image. The images displayed on the screen show no sign of color separation except near the edges of the screen. The image brightness on the screen is high enough that it can be watched in a normally illuminated room.
RESUMEN
One-way transmission of a multipixel image through the multimode optical fiber based on the phase-conjugation principle is realized. Adistortion-compensating hologram for each pixel of an image to be transmitted is superposed on a photoplate. Each hologram is recorded with a reference beam of different beam incidence angle to provide proper wave-front correction for each pixel without any interference from other pixels. The reference beams are holographically generated from a photoplate in which small holographic lenslets are aligned in a matrix pattern. Images of up to 25 pixels are transmitted through the fiber experimentally.
RESUMEN
It was found that the optimum subhologram dimension of the composite Fourier-transform hologram for minimizing image blur depends on object depth and information reduction ratio. Optimization of the subhologram dimension permits us to calculate the parameters of the composite Fourier-transform hologram for its applications to hologram transmission systems and to electroholographic three-dimensional displays.