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Pores are common defects generated during fabrication, which restrict the application of carbon/carbon (C/C) composites. To quantitatively understand the effects of pores on mechanical strength, this paper proposes a representative volume element model of unidirectional (UD) C/C composites based on the finite element method. The Hashin criterion and exponential degraded rule are used as the failure initiation and evolution of pyrolytic carbon matrices, respectively. Interfacial zones are characterized using the cohesive constitutive. At the same time, periodic boundary conditions are employed to study transverse tensile, compressive, and shear deformations of UD C/C composites. Predicted results are compared with the experimental results, which shows that the proposed model can effectively simulate the transverse mechanical behaviors of UD C/C composites. Based on this model, the effects of microstructural parameters including porosity, pore locations, the distance between two pores, pore clustering, and pore shapes on the mechanical strength are investigated. The results show that porosity markedly reduces the strength as porosity increases. When the porosity increases from 4.59% to 12.5%, the transverse tensile, compressive, and shear strengths decrease by 35.91%, 37.52%, and 30.76%, respectively. Pore locations, the distance between two pores, and pore clustering have little effect on the shear strength of UD C/C composites. For pore shapes, irregular pores more easily lead to stress concentration and matrix failure, which greatly depresses the bearing capacity of UD C/C composites.
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BACKGROUND: Cellular senescence is essential to TME development, progression, and remodeling. Few studies have examined cellular senescence in HCC after TACE. Investigating the relationship between cellular senescence, post-TACE prognosis, the TME, and immune treatment responses is crucial. METHODS: We analyzed the GSE104580 dataset to identify DEGs. A cellular senescence-related signature was developed using LASSO Cox regression in the GSE14520 dataset and validated in the ICGC dataset. High- and low-risk subgroups were compared using GSVA and GSEA. Correlation studies were conducted to explore the relationship between the prognostic model, immune infiltration, immunotherapy response, and drug sensitivity. RESULTS: A cellular senescence-related signature comprising FOXM1, CDK1, CHEK1, and SERPINE1 was created and validated. High-risk patients showed significantly lower OS than low-risk patients. High-risk patients had carcinogenetic pathways activated, immunosuppressive cells infiltrated, and immunomodulatory genes overexpressed. They also showed higher sensitivity to EPZ004777_1237 and MK-2206_1053 and potential benefits from GSK-3 inhibitor IX, nortriptyline, lestaurtinib, and JNK-9L. CONCLUSIONS: This study constructed a cellular senescence-related signature that could be used to predict HCC patients' responses to and prognosis after TACE treatment, aiding in the development of personalized treatment plans.
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A Kerr-lens mode-locked laser based on a Yb3+-doped disordered gadolinium scandate (Yb:GdScO3) crystal is reported for the first time, to the best of our knowledge. The crystal with the perovskite structure was grown using the Czochralski method, and its room temperature (RT) and low temperature (LT) spectra were also investigated. Due to the crystal's multisite structure (Gd3+/Sc3+ site), Yb:GdScO3 offers broad and intense polarized emission spectra in the near-infrared range (975-1075â nm). The stimulated emission cross section σSE is 0.46 × 10-20 cm2 at 1000â nm with an emission band width of 75.7â nm for E // b polarization. The continuous wave (CW) laser was operated pumped by a 976â nm fiber-coupled LD laser, resulting in a maximum output power of 8.74 W with a slope efficiency of 76.1% was obtained. Additionally, a pulses as short as 74 fs are generated at â¼1061.7â nm via Kerr-lens mode-locking. The average output power amounts to 32â mW at a pulse repetition rate of 101.4â MHz. All results indicate Yb:GdScO3 a promising candidate for 1â µm ultrashort laser.
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The utilization of mid-infrared (mid-IR) light spanning the 3-5â µm range presents notable merits over the 1.5â µm band when operating in adverse atmospheric conditions. Consequently, it emerges as a promising prospect for serving as optical carriers in free-space communication (FSO) through atmospheric channels. However, due to the insufficient performance level of devices in the mid-IR band, the capability of mid-IR communication is hindered in terms of transmission capacity and signal format. In this study, we conduct experimental investigations on the transmission of time-domain multiplexed ultra-short optical pulse streams, with a pulse width of 1.8 ps and a data rate of up to 40 Gbps at 3.6â µm, based on the difference frequency generation (DFG) effect. The mid-IR transmitter realizes an effective wavelength conversion of optical time division multiplexing (OTDM) signals from 1.5â µm to 3.6â µm, and the obtained power of the 40 Gbps mid-IR OTDM signal at the optimum temperature of 54.8â °C is 7.4 dBm. The mid-IR receiver successfully achieves the regeneration of the 40 Gbps 1.5â µm OTDM signal, and the corresponding regenerated power at the optimum temperature of 51.5â °C is -30.56â dBm. Detailed results pertaining to the demodulation of regeneration 1.5â µm OTDM signal have been acquired, encompassing parameters such as pulse waveform diagram, bit error rate (BER), and Q factor. The estimated power penalty of the 40 Gbps mid-IR OTDM transmission is 2.4â dB at a BER of 1E-6, compared with the back-to-back (BTB) transmission. Moreover, it is feasible by using chirped PPLN crystals with wider bandwidth to increase the data rate to the order of one hundred gigabits.
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We report on the demonstration of a pure Kerr-lens mode-locked Yb:CALYO laser which can directly deliver sub-200 fs pulses with more than 20-W average power. With an incident pump power of 89 W, 153-fs pulses were generated with an average power of 21.5â W at a repetition rate of 77.9â MHz. The corresponding peak power and single pulse energy were 1.6â MW and 0.27â µJ, respectively. The stable operation of the mode-locking was confirmed by very small fluctuations in both spectrum and output power recorded over an hour. Second harmonic generation (SHG) was conducted with 59% conversion efficiency, which indicated that the high-power mode-locking pulses are of good quality. Stable Kerr-lens mode-locking (KLM) with 156-fs pulse duration and 27.2-W average power was also achieved with 109-W pump power. To the best of our knowledge, this is the highest average output power ever reported from a femtosecond mode-locked bulk oscillator.
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The 3â¼5â µm mid-infrared (mid-IR) light has several exceptional benefits in the case of adverse atmospheric conditions compared to the 1.5â µm band, so it is a promising candidate for optical carriers for free-space communication (FSO) through atmospheric channels. However, the transmission capacity in the mid-IR band is constrained in the lower range due to the immaturity of its devices. In this work, to replicate the 1.5â µm band dense wavelength division multiplexing (DWDM) technology to the 3â µm band for high-capacity transmission, we demonstrate a 12-channel 150 Gbps FSO transmission in the 3â µm band based on our developed mid-IR transmitter and receiver modules. These modules enable wavelength conversion between the 1.5â µm and 3â µm bands based on the effect of difference-frequency generation (DFG). The mid-IR transmitter effectively generates up to 12 optical channels ranging from 3.5768â µm to 3.5885â µm with a power of 6.6 dBm, and each channel carries 12.5 Gbps binary phase shift keying (BPSK) modulated data. The mid-IR receiver regenerates the 1.5â µm band DWDM signal with a power of -32.1 dBm. Relevant results of regenerated signal demodulation have been collected in detail, including bit error ratio (BER), constellation diagram, and eye diagram. The power penalties of the 6th to 8th channels selected from the regenerated signal are lower than 2.2 dB compared with back-to-back (BTB) DWDM signal at a bit error ratio (BER) of 1E-6, and other channels can also achieve good transmission quality. It is expected to further push the data capacity to the terabit-per-second level by adding more 1.5â µm band laser sources and using wider-bandwidth chirped nonlinear crystals.
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In this paper, we demonstrated the direct amplification of femtosecond pulses with the Yb:CaYAlO4 crystal for the first time. A compact and simple two-stage amplifier delivered amplified pulses with the average powers of 55.4 W for σ-polarization and 39.4 W for π-polarization at the center wavelengthes of 1032â nm and 1030â nm, corresponding to 28.3% and 16.3% optical-to-optical efficiencies, respectively. These are to the best of our knowledge the highest value achieved with a Yb:CaYAlO4 amplifier. Upon using a compressor consisting of prisms and GTI mirrors, a pulse duration of 166-fs was measured. Thanks to the good thermal management, the beam quality (M2) parameters <1.3 along each axis were maintained in each stage.
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For underwater vehicles, the state of charge (SOC) of battery is often used to guide the optimal allocation of energy. An accurate SOC estimation can improve work efficiency and reliability of underwater vehicles. Model-based SOC estimation methods are still mainstream routes used in practical applications. Hence, accurate battery models are highly desirable, which depends not only on the circuit structure but also on the circuit parameters. Four-parameter identification algorithms, offline mechanism-based and least squared (LS) methods, as well as online recursive least-squares with forget factor (FFRLS) and extended Kalman filter (EKF) methods were analyzed in terms of SOC estimation under three different conditions. The results revealed that in the case without any disturbance, the predicted SOCs based on four-parameter identification circuits fitted well with the reference. Moreover, it is remarkable that the LS offline methods work better than the FFRLS online routes. In addition, the robustness has also been accessed through the other two conditions, i.e., measurement data with disturbance and initial SOC value with deviation. The results showed that maximum errors of SOC estimation based on the EKF approach are significantly lower than those of the other methods, and the values are 0.51% and 0.20%, respectively. Thus, the circuit model based on the EKF parameter identification approach possessed a stronger anti-interference performance during the SOC estimation process. This research can provide corresponding theoretical support on ECM parameter identification for lithium-ion batteries in underwater vehicles.
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In July 2021, an extreme precipitation event occurred in Henan, China, causing tremendous damage and deaths; so, it is very important to study the observation technology of extreme precipitation. Surface rain gauge precipitation observations have high accuracy but low resolution and coverage. Satellite remote sensing has high spatial resolution and wide coverage, but has large precipitation accuracy and distribution errors. Therefore, how to merge the above two kinds of precipitation observations effectively to obtain heavy precipitation products with more accurate geographic distributions has become an important but difficult scientific problem. In this paper, a new information fusion method for improving the position accuracy of satellite precipitation estimations is used based on the idea of registration and warping in image processing. The key point is constructing a loss function that includes a term for measuring two information field differences and a term for a warping field constraint. By minimizing the loss function, the purpose of position error correction of quantitative precipitation estimation from FY-4A and Integrated Multisatellite Retrievals of GPM are achieved, respectively, using observations from surface rain gauge stations. The errors of different satellite precipitation products relative to ground stations are compared and analyzed before and after position correction, using the '720' extreme precipitation in Henan, China, as an example. The experimental results show that the final run has the best performance and FY-4A has the worse performance. After position corrections, the precipitation products of the three satellites are improved, among which FY-4A has the largest improvement, IMERG final run has the smallest improvement, and IMERG late run has the best performance and the smallest error. Their mean absolute errors are reduced by 23%, 14%, and 16%, respectively, and their correlation coefficients with rain gauge stations are improved by 63%, 9%, and 16%, respectively. The error decomposition model is used to examine the contributions of each error component to the total error. The results show that the new method improves the precipitation products of GPM primarily in terms of hit bias. However, it does not significantly reduce the hit bias of precipitation products of FY-4A while it reduces the total error by reducing the number of false alarms.
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Lluvia , Tecnología , China , HumanosRESUMEN
The variation of polar vortex intensity is a significant factor affecting the atmospheric conditions and weather in the Northern Hemisphere (NH) and even the world. However, previous studies on the prediction of polar vortex intensity are insufficient. This paper establishes a deep learning (DL) model for multi-day and long-time intensity prediction of the polar vortex. Focusing on the winter period with the strongest polar vortex intensity, geopotential height (GPH) data of NCEP from 1948 to 2020 at 50 hPa are used to construct the dataset of polar vortex anomaly distribution images and polar vortex intensity time series. Then, we propose a new convolution neural network with long short-term memory based on Gaussian smoothing (GSCNN-LSTM) model which can not only accurately predict the variation characteristics of polar vortex intensity from day to day, but also can produce a skillful forecast for lead times of up to 20 days. Moreover, the innovative GSCNN-LSTM model has better stability and skillful correlation prediction than the traditional and some advanced spatiotemporal sequence prediction models. The accuracy of the model suggests important implications that DL methods have good applicability in forecasting the nonlinear system and vortex spatial-temporal characteristics variation in the atmosphere.
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We report on a 2-GHz high-power Kerr-lens mode-locked Yb:KGW laser pumped by a single-mode fiber laser. The output performance for two different output coupling rates was investigated. Stable bidirectional mode-locking operation at the repetition rate of 2.157â GHz was obtained with a 0.6% output coupler. The average output powers of bidirectional operation are 741â mW and 746â mW, with 123-fs and 126-fs pulse durations, respectively. By using a 1.6% output coupler, unidirectional mode-locking is achieved with 145-fs pulse duration and 1.7-W average output power, which, to the best of our knowledge, is the highest average power from Kerr-lens mode-locked GHz femtosecond oscillators.
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We reported a high-power pure Kerr-lens mode-locked Yb:CALYO laser based on the dual-confocal cavity delivering sub-100-fs pulses. The output pulses at 81 MHz have an average power of 10.4 W and the pulse duration of 98 fs, corresponding to the peak power of 1.14 MW. This is, to the best of our knowledge, the highest average power ever reported for a Kerr-lens mode-locked Yb-bulk oscillator. Analysis of the dual-confocal cavity was also conducted, which indicates a way to achieve higher average power. We believe the result described in this Letter may pave a way to develop Kerr-lens mode-locked bulk lasers with much higher average power.
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We demonstrate multi-cycle terahertz (MC-THz) generation in a 15.5 mm long periodically poled rubidium (Rb)-doped potassium titanyl phosphate (Rb:PPKTP) crystal with a poling period of 300 µm. By cryogenically cooling the crystal to 77 K, up to 0.72 µJ terahertz energy is obtained at a frequency of 0.5 THz with a 3 GHz bandwidth. A maximum internal optical-to-terahertz conversion efficiency of 0.16% is achieved, which is comparable with results achieved using periodically poled lithium niobate crystal. Neither photorefractive effects nor damage was observed with up to 900mJ/cm2, showing the great potential of Rb:PPKTP for multi-millijoule-level MC-THz generation.
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We demonstrated a diode-pumped high-power Kerr-lens mode-locked Yb:CaYAlO4 (Yb:CALYO) laser with a dual-confocal cavity, directly generating 59-fs pulses with 6.2 W average power, which is the highest average power from any sub-60 fs Yb-doped solid-state lasers. With the repetition rate of 50 MHz, the corresponding single pulse energy was 124 nJ and the peak power was 1.85 MW, which to the best of our knowledge is the highest peak power delivered directly from a sub-100 fs Yb-based bulk lasers ever.
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We report on a Kerr-lens mode-locked Yb:YSO lasers for the first time. Pumped by a single-mode fiber laser with high brightness and linear polarization, the Yb:YSO laser can deliver as high as 2 W average power with as short as 95 fs pulse duration at the repetition rate of 137.2 MHz, resulting in the single pulse energy of 14.8 nJ and the peak power of 155.7 kW. This work proves the potential on generation of sub-100 fs pulses with multi-watt level average power with the Yb doped oxyorthosilicates crystals.
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A high-power, high-repetition-rate, broadband tunable femtosecond optical parametric oscillator (OPO) is constructed based on KTiOAsO4 crystal, pumped by a 75.5 MHz mode-locked Yb:KGW laser. With 7 W pump power, the OPO generates as much as 2.32 W of signal power at 1.55 µm and 1.31 W of idler power at 3.05 µm, corresponding to a total conversion efficiency of 51.8%. Operating at 151 MHz repetition rate, the wavelength of the signal covers 1.41-1.71 µm with a tunable idler range of 2.61-3.84 µm. The idler bandwidth is more than 180 nm over the entire mid-infrared range. By compensating intracavity dispersion, the signal pulse has a nearly Fourier transform-limited duration of 129 fs at 1.52 µm.
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A collection of materials and device architectures are introduced for thin, stretchable arrays of ion sensors that mount on open cellular substrates to facilitate solution exchange for use in biointegrated electronics. The results include integration strategies and studies of fundamental characteristics in chemical sensing and mechanical response. The latter involves experimental measurements and theoretical simulations that establish important considerations in the design of low modulus, stretchable properties in cellular substrates, and in the realization of advanced capabilities in spatiotemporal mapping of chemicals' gradients. As the chemical composition of extracellular fluids contains valuable information related to biological function, the concepts introduced here have potential utility across a range of skin- and internal-organ-integrated electronics where soft mechanics, fluidic permeability, and advanced chemical sensing capabilities are key requirements.
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We report on an efficient high-power, widely tunable femtosecond optical parametric oscillator in BiB3O6, synchronously pumped by a frequency-doubled mode-locked Yb:KGW laser at 515 nm. Using collinear type I (oâe+e) phase matching, a resonant wavelength range of 688-1057 nm at a 151-MHz repetition rate is demonstrated, with a tunable idler range of 1150-1900 nm. The output power at 705 nm is 1.09 W for 3.6 W pump power exceeding 30% conversion efficiency. Near-transform-limited pulses down to 71 fs are achieved by deploying extracavity dispersion compensation in a pair of SF6 prisms.
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Femtosecond optical pulses have applications in optical communication, astronomical frequency combs, and laser spectroscopy. Here, a hybrid mode-locked erbium-doped fiber (EDF) laser with topological insulator (TI) is proposed, for the first time to our best knowledge. The pulsed laser deposition (PLD) method is employed to fabricate the fiber-taper TI saturable absorber (TISA). By virtue of the fiber-taper TISA, the hybrid EDF laser is passively mode-locked using the nonlinear polarization evolution (NPE), and emits 70 fs pulses at 1542 nm, whose 3 dB spectral width is 63 nm with a repetition rate and transfer efficiency of 95.4 MHz and 14.12%, respectively. Our experiments indicate that the proposed hybrid mode-locked EDF lasers have better performance to achieve shorter pulses with higher power and lower mode-locking threshold in the future.
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We report a multi-gigahertz (GHz) repetition-rate femtosecond MgO:PPLN optical parametric oscillator (OPO) harmonically pumped by a 75.6 MHz Kerr-lens mode-locked Yb:KGW laser. By fractionally increasing the OPO cavity length, we obtained OPO operation up to the 493rd harmonic of the pump laser repetition rate, corresponding to a repetition rate as high as 37.3 GHz. Using a 1.5% output coupler, we are able to extract signal pulses with up to 260 mW average power at the 102nd harmonic (7.7 GHz) and 90 mW at the 493rd harmonic (37.3 GHz) under 2 W pump power. The measured relative standard deviations of the fundamental and the 102nd harmonic signal power were recorded to be 0.5% and 2.1%, respectively. The signal pulse durations at different harmonics were measured in the range of 160-230 fs.