Modified Micromarsupialization as Treatment of Ranula in a Pediatric Patient.

Ranulas are mucoceles located on the floor of the mouth. The main form of treatment for these lesions is surgical excision, but this can lead to complications such as hemorrhage, recurrence of the lesion, and damage to the lingual nerve. Thus, other therapeutic modalities are indicated, such as modified micromarsupialization, which is a simple technique and not associated with recurrences, and without the need of a new intervention in the postoperative period. An 11-year-old female child, nonwhite, presented with bubble-shaped lesion located on floor of the mouth, on the left side, with exophytic growth, sessile base, bluish coloration, measuring about 4.0 cm in diameter, showing well-defined limits, well-delimited contours and borders, smooth surface, and softened consistency. Under the diagnostic hypothesis of the ranula, a modified micromarsupialization was performed. After 90 days of observation, complete regression and repair of the lesion were observed, without recurrence. Modified micromarsupialization is a simple therapeutic modality, low cost, and well-tolerated by the patient, mainly the pediatric one, being considered very effective in the treatment of lesions of difficult clinical management, as the ranula.

Florid cemento-osseous dysplasia and peripheral giant cell granuloma in a patient with neurofibromatosis 1.

We report a 35-year-old mulatto female patient with neurofibromatosis Type 1 who presented with facial asymmetry. The patient had two lesions: florid cemento-osseous dysplasia associated with peripheral giant cell granuloma. She was referred for surgical treatment of the peripheral giant cell granuloma and the florid cemento-osseous dysplasia was treated conservatively by a multidisciplinary team. So far, no changes have been observed in the patient's clinical status. We observed no recurrence of peripheral giant cell granuloma. To the best of our knowledge, the present case is the first report of a patient with neurofibromatosis Type 1 associated with a giant cell lesion and florid cemento-osseous dysplasia.

Florid cemento-osseous dysplasia and peripheral giant cell granuloma in a patient with neurofibromatosis 1

Abstract: We report a 35-year-old mulatto female patient with neurofibromatosis Type 1 who presented with facial asymmetry. The patient had two lesions: florid cemento-osseous dysplasia associated with peripheral giant cell granuloma. She was referred for surgical treatment of the peripheral giant cell granuloma and the florid cemento-osseous dysplasia was treated conservatively by a multidisciplinary team. So far, no changes have been observed in the patient's clinical status. We observed no recurrence of peripheral giant cell granuloma. To the best of our knowledge, the present case is the first report of a patient with neurofibromatosis Type 1 associated with a giant cell lesion and florid cemento-osseous dysplasia.

Accuracy of two cephalometric analyses in the treatment of patients with skeletal class III malocclusion.

The aim of the present study was to compare the treatment plan outlined from the diagnosis obtained by two different cephalometric analyses with the clinical decision made for surgical treatment of patients with skeletal Class III malocclusion. For this purpose, 82 skeletal Class III patients were evaluated, divided into three groups according to the surgical procedure performed for dentofacial deformity correction. Their preoperative cephalometric radiographs were submitted to McNamara and Steiner cephalometric analyses. The association of variables was evaluated by Kappa correlation (α=5%). The agreement between indication of surgical procedures performed based on clinical decision and surgical treatment indicated based on the evaluation of McNamara and Steiner cephalometric analyses were not significant (p=0.609 and p=0.544, respectively). McNamara and Steiner analyses showed reasonable agreement with each other as to the diagnosis, but did not agree with the clinical decision to treat skeletal CIII patients. Both tests were equally inaccurate in the indication of the surgical treatment.

Accuracy of Two Cephalometric Analyses in the Treatment of Patients with Skeletal Class III Malocclusion

The aim of the present study was to compare the treatment plan outlined from the diagnosis obtained by two different cephalometric analyses with the clinical decision made for surgical treatment of patients with skeletal Class III malocclusion. For this purpose, 82 skeletal Class III patients were evaluated, divided into three groups according to the surgical procedure performed for dentofacial deformity correction. Their preoperative cephalometric radiographs were submitted to McNamara and Steiner cephalometric analyses. The association of variables was evaluated by Kappa correlation (α=5%). The agreement between indication of surgical procedures performed based on clinical decision and surgical treatment indicated based on the evaluation of McNamara and Steiner cephalometric analyses were not significant (p=0.609 and p=0.544, respectively). McNamara and Steiner analyses showed reasonable agreement with each other as to the diagnosis, but did not agree with the clinical decision to treat skeletal CIII patients. Both tests were equally inaccurate in the indication of the surgical treatment.

O objetivo deste trabalho foi comparar o plano de tratamento delineado a partir do diagnóstico obtido através de duas análises cefalométricas distintas, com a decisão clínica tomada para o tratamento cirúrgico de pacientes portadores de maloclusão classe III esquelética. Para isto foram avaliados 82 pacientes classe III esquelética, divididos em três grupos de acordo com o procedimento cirúrgico realizado para a correção da deformidade dentofacial. Suas radiografias cefalométricas pré-operatórias foram submetidas à análise cefalométrica de McNamara e de Steiner. A associação das variáveis foi avaliada pelo teste de correlação de Kappa (α=5%). A concordância entre a indicação do tratamento cirúrgico baseado na decisão clínica e o tratamento cirúrgico proposto a partir da avaliação das análises de McNamara e de Steiner não foi significante (p=0,6094 e p=0,5442,respectivamente). As análises de McNamara e de Steiner apresentaram concordância razoável entre si para o diagnóstico, porém não apresentam concordância com a decisão clínica para o tratamento de pacientes CIII esquelética, sendo as duas análises igualmente imprecisas na indicação do tratamento cirúrgico dos pacientes da amostra.

Levantamento epidemiológico dos casos de câncer de boca em um hospital de referência em Campina Grande, Paraíba, Brasil / Epidemiological survey of oral cancer cases in a reference hospital of Campina Grande, state of Paraíba, Brazil

Objetivo: Determinar dados epidemiológicos e analisar variáveis relacionadas ao paciente, ao tipo histológico, localização anatômica da lesão, hábitos bucais, estadiamento clínico e à classificação do tratamento do pacientes com câncer de boca, atendidos num Hospital de referência, na cidade de Campina Grande-PB. Método: Foi realizada coleta de dados em prontuários de todos os pacientes portadores de neoplasia maligna de boca, diagnosticada entre 1999 e 2008, sendo submetidos à análise estatística descritiva. Resultados: Do total da amostra de 473 casos de câncer bucal foi observado que 62,71% eram do gênero masculino e 59,96% eram leucodermas. A idade dos pacientes variou de 07 a 90 anos, com média de 65,5±13. O carcinoma espinocelular foi o tipo histológico mais prevalente (86,20%), seguido por carcinoma mucoepidermóide (5,10%), adenocarcinoma (2,10%), carcinoma metastático e linfoma não Hodking com (1,70%) cada. A língua foi localização anatômica mais comum do carcinoma espinocelular (29,60%). A maioria das lesões foi diagnosticada em estádios clínicos III e IV. A presença de hábitos nocivos foi observada em 78,81% dos casos analisados, sendo a associação fumo/consumo de bebidas a mais prevalente (50,00%). O tratamento antineoplásico mais empregado foi a combinação cirurgia e radioterapia (38,10%). Conclusão: Diante dos resultados da amostra avaliada, conclui-se que o câncer bucal atinge preferencialmente indivíduos leucodermas, do gênero masculino, com hábitos de tabagismo e etilismo ou associação dos dois. O carcinoma espinocelular com localização lingual e diagnosticado em estádio clínico avançado foi o tipo histológico mais frequente. A combinação de cirurgia e radioterapia foi a terapia antineoplásica mais empregada.

Objective: To collect epidemiological data and analyze variables related to the patient, histological type, anatomical location of the lesion, oral habits, clinical staging and treatment classification of patients with oral cancer seen at a reference hospital in the city of Campina Grande, PB, Brazil. Methods: Data were collected from medical records of all patients with malignant neoplasm of the mouth diagnosed between 1999 and 2008, and subjected to descriptive statistical analysis. Results: The total sample consisted of 473 cases of oral cancer, 62.71% of which were male patients and 59.96% of which were Caucasians. The ages of the patients ranged from 7 to 90 years (mean age = 65.5 ± 13). Squamous cell carcinoma was the most prevalent histological type (86.20%), followed by mucoepidermoid carcinoma (5.10%), adenocarcinoma (2.10%), metastatic carcinoma (1.70%) and non-Hodgkin's lymphoma (1.70%). The tongue was the most common anatomical location of squamous cell carcinoma (29.60%). Most injuries were diagnosed in the stages III and IV. The presence of deleterious habits was observed in 78.81% of the cases, with the association of smoking / drinking being the most prevalent (50.00%). The most used anticancer treatment was the combination of surgery and radiotherapy (38.10%). Conclusion: Given the results of the studied sample, it can be concluded that oral cancer primarily affects Caucasian male individuals with smoking and drinking habits or the association of both. Squamous cell carcinoma of the tongue, diagnosed at an advanced clinical stage, was the most frequent histological type. Combination of surgery and radiotherapy was the most frequent anticancer therapy.

Associação entre líquen plano bucal e infecção pelo vírus da hepatite C: [revisão] / Association between oral lichen planus and hepatitis C virus infeccion: [review]

Objetivo: apresentar uma revisão da literatura sobre as evidências de implicação do Vírus da Hepatite C (VHC) na etiologia do líquen plano bucal (LPB), abordando alguns aspectos deste controverso tema. Material e métodos: foi realizada uma pesquisa bibliográfica através da Biblioteca Virtual em Saúde (BVS), identificando-se artigos publicados nas revistas indexadas nas seguintes bases de dados: BBO, LILACS e MEDLINE. De forma combinada utilizaram-se como descritores: hepatite C, líquen plano bucal e leucoplasia, considerando o intervalo de tempo de 10 anos (entre 1998 e 2008) e os idiomas: Português, Inglês e Espanhol. Dessa forma, foram incluídas 30 publicações. Resultados: verificou-se que a associação entre a infecção do HCV e o LPB foi investigada, mas a maioria dos resultados foi inconsistente. Conclusão: considerando os resultados obtidos estudos adicionais são recomendados para provar as hipóteses atuais a respeito da associação e da patogênese do líquen plano bucal à infecção pelo HCV.

Objective: to present a literature review of the evidence of involvement of the Hepatitis C Virus (HCV) in the etiology of oral lichen planus (OLP), addressing some aspects of this controversial topic. Material and methods: we performed a literature search through the Virtual Health Library (VHL), identifying articles published in journals indexed in the following databases: BBO, LILACS and MEDLINE. In combination were used as descriptors: hepatitis C, lichen planus and leukoplakia, considering the time span of 10 years (between 1998 and 2008) and languages: Portuguese, English and Spanish. Thus, 30 publications were included. Results: it was found that the association between HCV infection and the LPB was investigated, but most results were inconsistent. Conclusion: the results, additional studies are recommended to prove the current hypotheses about the association and the pathogenesis of lichen planus with HCV infection.

Marcadores biológicos e etiopatogenia do Líquen plano bucal / Association of removable partial prothesis with the fixed prothesis: a literature rewiew

O Líquen Plano Bucal (LPB) é uma doença mucocutânea inflamatória crônica que clinicamente apresenta-se de variadas formas como reticular, atrófica ou eritematosa e erosiva. Sua etiologia é desconhecida, embora seja considerada como uma doença auto-imune. As citocinas produzidas e liberadas por células do infiltrado inflamatório presentes no LPB são importantes para o recrutamento de novos linfócitos para o local da lesão e são capazes de estimular e inibir produção de novas citocinas sendo essenciais para exacerbação e perpetuação do LPB. O objetivo deste trabalho é fazer uma revisão de literatura sobre os marcadores biológicos e a etiopatogenia do LPB.

The Oral Lichen Planus (OLP) is a chronic inflammatory mucocutaneous disease that clinically presents itself in many ways as reticular, atrophic or erythematous and erosive. Its etiology is unknown, although it is considered as an autoimmune disease. Cytokines produced and released by inflammatory cells present in the OLP are important for the recruitment of new cytokines are essential for the perpetuation and exacerbation of OLP. The objective of this study is to review the literature on biological markers and the pathogenesis of OLP.