1.
Chem Commun (Camb)
; 54(60): 8312-8315, 2018 Jul 24.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29868665
RESUMO
One cyclopalladated ferrocene compound CP was synthesized, which showed a good cell cytotoxicity. Assisted by a dual-targeting drug delivery system, the anticancer activity of CP to MDA-MB-468 remained unchanged, but the toxicity to non-tumorigenic cell line NIH3T3 was remarkably reduced. This provided a new path for the development of cyclopalladated ferrocene as an antitumor drug candidate.