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1.
R. bras. Reprod. Anim. ; 40(4): 595-596, Out-Dez. 2016. tab
Artigo em Português | VETINDEX | ID: vti-24229

Resumo

The Richeria grandis known is for its aphrodisiac properties and due to its wide empiric use well as thelack of gender Richeria studies the objective of this study was to evaluate the androgenic and anti-androgenicactivity of this plant. They were used in this study 64 male Wistar rats, castrated, divided into eight groups. Thegroups for the study of androgen activity were treated with boiling water over corn R. grandis ethanolic extractoil at doses of 75, 150 and 300 mg / kg and groups of antiandrogenic activity received corn oil, distilled waterand ethanol extract at doses of 75, 150 and 300 mg / kg associated with testosterone. It was found that theethanol extract of R. grandis in the tested doses did not differ statistically from the negative and positive controlsdid not thus demonstrating androgenic activity or antiandrogenic.(AU)


Assuntos
Animais , Ratos , Malpighiales/anatomia & histologia , Malpighiales/química , Malpighiales/fisiologia , Androgênios/administração & dosagem , Androgênios/análise , Antagonistas de Androgênios/análise
2.
Rev. bras. reprod. anim ; 40(4): 595-596, Out-Dez. 2016. tab
Artigo em Português | VETINDEX | ID: biblio-1492402

Resumo

The Richeria grandis known is for its aphrodisiac properties and due to its wide empiric use well as thelack of gender Richeria studies the objective of this study was to evaluate the androgenic and anti-androgenicactivity of this plant. They were used in this study 64 male Wistar rats, castrated, divided into eight groups. Thegroups for the study of androgen activity were treated with boiling water over corn R. grandis ethanolic extractoil at doses of 75, 150 and 300 mg / kg and groups of antiandrogenic activity received corn oil, distilled waterand ethanol extract at doses of 75, 150 and 300 mg / kg associated with testosterone. It was found that theethanol extract of R. grandis in the tested doses did not differ statistically from the negative and positive controlsdid not thus demonstrating androgenic activity or antiandrogenic.


Assuntos
Animais , Ratos , Androgênios/administração & dosagem , Androgênios/análise , Antagonistas de Androgênios/análise , Malpighiales/anatomia & histologia , Malpighiales/fisiologia , Malpighiales/química
3.
R. bras. Reprod. Anim. ; 40(4): 611-612, Out-Dez. 2016. tab
Artigo em Português | VETINDEX | ID: vti-24289

Resumo

The aim of this study was to evaluate the reproductive organs on the effect of Simarouba versicolorethanol extract (EEOH-Sv) at a dose of 10mg / kg administered for 60 days / VO. The testes, epididymis,prostate and seminal vesicles were sectioned and placed in vials Boan solution for 24 hours and then preservedin alcohol at 70%. Histopathology of organs were dehydrated in xylol, impregnated and embedded in paraffin.Subsequently cut in the microtome at a thickness of 3 m and subjected to hematoxylin-eosin. The results of thehistopathology of the testis was observed that the EEOH-Sv caused concretions in 100% of animals evaluatedand 20% of the animals showed sharp associated with degeneration of the seminiferous tubules. In theepididymis was observed in 40% epithelial thickening, and there was 100% of benign prostatic hypertrophyassociated in 20% of animals inflammatory infiltrate. Thus, it is concluded that-Sv EEOH was toxic to thisorgans except the seminal vesicle.(AU)


Assuntos
Animais , Ratos , Genitália/anatomia & histologia , Genitália/fisiopatologia , Ratos/anatomia & histologia , Testes de Toxicidade Crônica/análise , Etanol/efeitos adversos , Simarouba/efeitos adversos
4.
Rev. bras. reprod. anim ; 40(4): 611-612, Out-Dez. 2016. tab
Artigo em Português | VETINDEX | ID: biblio-1492408

Resumo

The aim of this study was to evaluate the reproductive organs on the effect of Simarouba versicolorethanol extract (EEOH-Sv) at a dose of 10mg / kg administered for 60 days / VO. The testes, epididymis,prostate and seminal vesicles were sectioned and placed in vials Boan solution for 24 hours and then preservedin alcohol at 70%. Histopathology of organs were dehydrated in xylol, impregnated and embedded in paraffin.Subsequently cut in the microtome at a thickness of 3 m and subjected to hematoxylin-eosin. The results of thehistopathology of the testis was observed that the EEOH-Sv caused concretions in 100% of animals evaluatedand 20% of the animals showed sharp associated with degeneration of the seminiferous tubules. In theepididymis was observed in 40% epithelial thickening, and there was 100% of benign prostatic hypertrophyassociated in 20% of animals inflammatory infiltrate. Thus, it is concluded that-Sv EEOH was toxic to thisorgans except the seminal vesicle.


Assuntos
Animais , Ratos , Genitália/anatomia & histologia , Genitália/fisiopatologia , Ratos/anatomia & histologia , Testes de Toxicidade Crônica/análise , Etanol/efeitos adversos , Simarouba/efeitos adversos
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