Necrotizing Soft Tissue Infection In Dog Case Report

Necrotizing soft tissue infections (NSTI) are diseases that can affect the skin, subcutaneous tissue, superficial fascia, and occasionally, deep fascia, muscle tissue and adipose tissue. They present states of necrosis, which can lead to systemic toxicity and high rates of mortality. This paper describes the occurrence of a NSTI in a six year-old female beagle. The animal presented pain, areas of edema, erythema, loss of sensitivity and crepitations, in the right flank, from the dorso-lumbar area to the mammary gland. In the bacterial culture, Staphylococcus pseudintermedius and Group B Streptococcus, were isolated. The biopsy revealed necrotizing cellulites. Treatment was administered with ceftriaxone (50 mg/kg IV 12/12h), metronidazole (25 mg/kg 12/12h), and tramadol clorhidrate (4 mg/kg IV 8/8h). Wound treatment included extensive cleanings, every twelve hours, with warm diluted iodopovidone (0,01%) and compressive bandages. The diagnosis and early treatment of this disease allows a better prognosis for affected animals.

Necrotizing Soft Tissue Infection In Dog Case Report

Necrotizing soft tissue infections (NSTI) are diseases that can affect the skin, subcutaneous tissue, superficial fascia, and occasionally, deep fascia, muscle tissue and adipose tissue. They present states of necrosis, which can lead to systemic toxicity and high rates of mortality. This paper describes the occurrence of a NSTI in a six year-old female beagle. The animal presented pain, areas of edema, erythema, loss of sensitivity and crepitations, in the right flank, from the dorso-lumbar area to the mammary gland. In the bacterial culture, Staphylococcus pseudintermedius and Group B Streptococcus, were isolated. The biopsy revealed necrotizing cellulites. Treatment was administered with ceftriaxone (50 mg/kg IV 12/12h), metronidazole (25 mg/kg 12/12h), and tramadol clorhidrate (4 mg/kg IV 8/8h). Wound treatment included extensive cleanings, every twelve hours, with warm diluted iodopovidone (0,01%) and compressive bandages. The diagnosis and early treatment of this disease allows a better prognosis for affected animals.(AU)

Contaminação fúngica no leite humano e em sítios anatômicos de lactantes e lactentes / Fungal contamination in human milk and in the anatomic sites of breastfeeding mothers and infants

As infecções bacterianas ou fúngicas causam quadro clínico de mastite, que motiva desmame precoce. Os micro-organismos patogênicos, como leveduras do gênero Candida , quando em número elevado no intestino, podem causar disbiose. Nesta pesquisa, foram realizadas a detecção e a identificação de microbiota fúngica nas amostras de leite humano e de sítios anatômicos de mulheres e crianças atendidas pelo Banco de Leite Humano do Instituto Fernandes Figueira. A virulência dos isolados de levedura foi determinada pelos testes de atividade proteolítica. De 64 amostras analisadas, 81% foram positivas para fungos, com maior prevalência de Candida albicans (73%), seguida do complexo C. parapsilosis (15,4%). Perfis semelhantes aos verificados no total de amostras foram encontrados nas amostras de leite, nas mamas e na cavidade oral, sugerindo-se a ocorrência de associação entre a infecção cutânea da mãe e do lactente com o leite ingerido. O perfil associado à virulência dos isolados de Candida foi determinado pelo teste de produção de proteases, e 100% das amostras mostraram resultados fortemente positivos, indicando alto grau de infecciosidade . A alta prevalência de C. albicans nas amostras coletadas de mamas, no leite e na cavidade oral, é importante fator de risco à saúde de lactentes.(AU)

Bacterial or fungal infections might produce a clinical feature of mastitis, which is one of the main causes of precocious breast-feeding discontinuity. In addition, when the potentially pathogenic microorganisms as yeast of Candida genera were in high counting in the intestine, might cause dysbiosis. This study aimed detecting and identifying fungi in human milk and anatomical sites of breast-feeding women and infants who were enrolled at Human Milk Bank of the Institute Fernandes Figueira. The virulence of the yeast isolates was evaluated by means of proteolytic activity tests. Eight-one percent of 64 analyzed samples showed positive results to fungi, with a highest prevalence of Candida albicans (73%) followed by C. parapsilosis complex (15.4%). Similar profiles were found in samples of milk, of breasts and of infants mouth cavity, suggesting a correlation between breast-feeding mothers and infants cutaneous infections with the ingested milk. The virulence of the isolated Candida was determined by the proteolytic activity test. All of the isolates (100%) were strongly positive, indicating a high degree of infectivity. The high prevalence of C. albicans in samples collected from breasts, mouth cavity and milk is a crucial risk factor for the infants health.(AU)