Hernioplasty with polypropylene implant after an abdominal trauma of a pregnant cat

The incidence of accidents with cats and its consequences on the health of these animals have been reported frequently in the literature. The abdominal hernia is an example of a condition developed as a result of trauma. Abdominal hernia is a defect of the inner wall of the abdomen that can allow part of the abdominal contents to protrude. In this case report, a pregnant cat has developed an abdominal hernia after disappearing for a week. The animal was clinically well, but the abdominal volume was considerable. Surgical intervention was necessary as soon as possible, because it was an irreducible hernia. A significant amount of devitalized muscle tissue and fragile tissue were observed. Because of the abdominal necrosis, there was no possibility to perform conventional suturing technique in the abdominal wall to correct the hernia. It was necessary to apply a polypropylene mesh implant, which is anchored by means of simple interrupted stitches. Besides hernioplasty, a lumpectomy and ovariohysterectomy were performed due to the presence of a suppurative inflammation of the mammary glands and fetal maceration in the uterus. The review of the patient, after 10 days, revealed no signs of infection of the surgical wound and the implant remained stable. The patient continued feeding and drinking water normally. The goal of this study is to describe the surgical technique of hernia repair using polypropylene implant in a cat that has lost approximately 50% of the abdominal muscle tissue caused by an abdominal trauma.

Hernioplasty with polypropylene implant after an abdominal trauma of a pregnant cat

The incidence of accidents with cats and its consequences on the health of these animals have been reported frequently in the literature. The abdominal hernia is an example of a condition developed as a result of trauma. Abdominal hernia is a defect of the inner wall of the abdomen that can allow part of the abdominal contents to protrude. In this case report, a pregnant cat has developed an abdominal hernia after disappearing for a week. The animal was clinically well, but the abdominal volume was considerable. Surgical intervention was necessary as soon as possible, because it was an irreducible hernia. A significant amount of devitalized muscle tissue and fragile tissue were observed. Because of the abdominal necrosis, there was no possibility to perform conventional suturing technique in the abdominal wall to correct the hernia. It was necessary to apply a polypropylene mesh implant, which is anchored by means of simple interrupted stitches. Besides hernioplasty, a lumpectomy and ovariohysterectomy were performed due to the presence of a suppurative inflammation of the mammary glands and fetal maceration in the uterus. The review of the patient, after 10 days, revealed no signs of infection of the surgical wound and the implant remained stable. The patient continued feeding and drinking water normally. The goal of this study is to describe the surgical technique of hernia repair using polypropylene implant in a cat that has lost approximately 50% of the abdominal muscle tissue caused by an abdominal trauma.(AU)

Treatment of abdominal wall hernia with suture, or polypropylene, or collagen prosthesis

PURPOSE:To develop an experimental model for incisional hernias and to compare morphological and functional aspects of hernia repairs by suture, polypropylene mesh and collagen mesh.METHODS:A defect measuring 7cm x 2cm was created in the anterior abdominal of 28 New Zealand male rabbits, divided into four groups (n = 7): (1) control, (2) suture of the anterior sheath of the rectus abdominal muscle, (3) setting of polypropylene mesh, and (4) setting of collagen mesh. On the 90th postoperative day, the animals were examined to verify the presence of incisional hernia. Samples of abdominal wall and scar were collected for histological study.RESULTS:Incisional hernia was identified in 85.7% of the control group, 57.1% of the suture group, 42.9% of the collagen mesh group, and none in the polypropylene mesh group (p = 0.015). Mesh exposure could be identified in 71.4% of the animals in group 3 and in no animal in group 4 (p = 0.021). The polypropylene mesh is effective in the treatment of abdominal wall defects, causing an intense inflammatory reaction.CONCLUSION:The collagen mesh is biocompatible, producing a minimal inflammatory reaction, but fails in the treatment of abdominal wall defects.(AU)

Nonwoven polypropylene prosthesis in large abdominal wall defects in rats / Tela de polipropileno sem tecelagem na correção de grandes defeitos da parede abdominal em ratos

PURPOSE: To evaluate, in large abdominal wall defects surgically shaped in rats, if a synthetic polypropylene nonwoven prosthesis could be used as a therapeutic option to conventional polypropylene mesh. METHODS: Twenty four (24) Wistar rats were enrolled into three groups. Group 1 (Simulation group) with an abdominal wall defect of 3 X 3 left untreated and Groups 2 and 3, respectively treated with a conventional polypropylene mesh and a polypropylene nonwoven (NWV) prosthesis to cover the breach. At the 45th postoperatively day, adhesion (area and strength) and vascularization of Groups 2 and 3 were evaluated. The histological preparations with Hematoxylin-Eosin, Tricromium of Masson, Pricrosirius red and polarization with birefringence, and also the structural analysis of the prostheses carried on by Thermogravimetry and Differential Scanning Calorimetry were also assessed. RESULTS: There were no significant differences between the Groups 2 and 3. CONCLUSION: In rats, the polypropylene nonwoven prosthesis showed to be safe and has to be considered as an alternative to conventional mesh manufactured by weaving in the treatment of great defects of the abdominal wall.(AU)

OBJETIVO: Avaliar, em grandes defeitos da parede abdominal produzidos cirurgicamente em ratos, se uma prótese sintética de polipropileno sem tecelagem poderia ser utilizada como alternativa terapêutica às telas convencionais de polipropileno. MÉTODOS: Vinte e quatro ratos foram distribuídos em três grupos numericamente iguais. Grupo 1 (Simulação), no qual um defeito de 3 x 3 cm foi constituído na parede abdominal sem tratamento. Uma tela convencional de polipropileno e uma tela de polipropileno sem tecelagem foram colocadas para cobrir o defeito, nos grupos 2 e 3 , respectivamente. No 45º dia de pós-operatório foram avaliadas a área e a força das aderências, além da vascularização. Também foram analisados os preparados histológicos com Hematoxilina-eosina, Tricrômio de Masson e Picrosirius com polarização e birrefringência, além de efetuada análise estrutural da prótese mediante Termogavimetria e Colorimetria Exploratória Diferencial. RESULTADOS: Não houve diferença significante entre os grupos 2 e 3. CONCLUSÃO: Em ratos, a tela de polipropileno sem tecelagem mostrou ser segura e deve ser considerada como uma alternativa à tela convencional manufaturada por tecelagem, no tratamento dos grandes defeitos da parede abdominal.(AU)

2-hydroxyethyl methacrylate composite - polypropylene mesh for preventing peritoneal adhesions in female dogs / Compósito 2-hidroxietil dimetacrilato-tela de polipropileno para prevenção de aderências peritoneais em cadelas

PURPOSE: To evaluate whether the lining facing the visceral side of polypropylene mesh made with 2-hydroxyethyl methacrylate (p(HEMA)) hydrogel could avoid peritoneal adhesion in female dogs. METHODS: Eight animals (group PP) had a polypropylene mesh implanted to correct a defect in the rectal abdominal muscle, whereas in the other group (group PH) the polypropylene mesh was coated with p(HEMA) composite on the surface facing the peritoneal area. RESULTS: Adhesions were observed on the mesh in 62.5 percent of the PP group. In the PH group adhesions were present only on the suture lines. CONCLUSION: p(HEMA) hydrogel was well tolerated and effective in avoiding visceral and omental adhesions on the surface of the polypropylene mesh.(AU)

OBJETIVO: Avaliar se o revestimento da face visceral de uma tela de polipropileno com 2-hidroxietil dimetacrilato (p(HEMA)) poderia evitar aderências peritoniais em cadelas. MÉTODOS: Em oito animais (Grupo PP) foram implantadas telas de polipropileno para correção de um defeito do músculo reto abdominal, enquanto em outro grupo (Grupo PH) fez-se a implantação de uma tela de polipropileno cuja face peritonial foi revestida por 2-hidroxietil dimetacrilato (p(HEMA)). RESULTADOS: Foram observados 62,5 por cento de aderências peritoniais sobre a tela nos animais do Grupo PP, enquanto que no Grupo PH estas não ocorreram, exceto sobre a linha se sutura. CONCLUSÃO: O hidrogel de p(HEMA) foi bem tolerado pelos animais e mostrou-se efetivo na prevenção das aderências viscerais e omentais sobre a tela de polipropileno.(AU)

Evaluation of peritoneal adhesions formation and tissue response to polypropylene - poli (2-hydroxyethyl methacrylate)-(polyHEMA) implant on rats' abdominal wall / Avaliação da formação de aderências peritoneais e da resposta tecidual ao implante de poli (2-hidroxietil dimetacrilato)-(poliHEMA) na parede abdominal de ratos

PURPOSE: To verify if the composit poli (2-hydroxyethyl methacrylate)-PolyHEMA/polypropylene mesh implanted in the female rat's abdominal wall could be suitable for the prevention of peritoneal adhesions, and for the evaluation of the tecidual response produced by this biomaterial. METHODS: Polypropylene meshes (Group PP, n=20) and polypropylene meshes coated with a layer of poli (2-hydroxyethyl methacrylate)-PolyHEMA (Group PH, n=20) were implanted on the abdominal wall of Wistar female rats. Ten animals from each group were submitted to euthanasia at 15 and 30 days of the postoperative period. RESULTS: The animals from the group PP presented visceral adhesions on the mesh surface, which was not observed in the ones from group PH. At the histopathological examination foreign body response was observed in both groups, whilst there was a greater intensity of inflammatory response in group PH on both moments. CONCLUSION: The poli (2-hydroxyethyl methacrylate) polyHEMA hydrogel associated to polypropylene mesh reduces visceral adhesion formation in rats, although it may be associated to greater inflammatory reaction.(AU)

OBJETIVO: Verificar se compósito poli 2-hidroxietil dimetacrilato (PoliHEMA) / tela de polipropileno implantado na parede abdominal de ratas seria adequado para prevenção de aderências peritoneais e avaliar a resposta tecidual desencadeada por este biomaterial. MÉTODOS: Foram implantadas telas de polipropileno - Grupo PP (n=20) e telas de polipropileno revestidas por uma camada de poli 2 (hidroxietil dimetacrilato)-PolyHEMA - Grupo PH (n=20) na parede abdominal de ratas da linhagem Wistar. Dez animais de cada grupo foram submetidos à eutanásia aos 15 e 30 dias de pós-operatório. RESULTADOS: Os animais do grupo PP apresentaram aderências viscerais na superfície da tela, o que não foi observado nos do grupo PH. Observou-se no exame histopatológico resposta tipo corpo estranho nos dois grupos sendo que no grupo PH houve maior intensidade de resposta inflamatória nos dois momentos. CONCLUSÃO: O hidrogel de poliHEMA quando associado à tela de polipropileno reduz a formação de aderências viscerais em ratos, embora possa estar associado à reação inflamatória mais intensa.(AU)

The optical analysis of the abdominal wall using the biospeckle after implants of polypropylene mesh in rats / Análise ótica da parede abdominal pelo biospeckle após implante de prótese de polipropileno em ratos

PURPOSE: To evaluate an experimental animal model to study the abdominal tissue activity considering its interaction with a polypropylene mesh, through the use of one of the optical phenomena of light Laser, the biospeckle. METHODS: Fifty Wistar male rats were divided into four groups: Group 1: ten animals not submitted to surgery; Group 2: ten animals submitted to surgery without polypropylene mesh; Group 3: 20 animals submitted to surgery followed by the mesh placement; Group 4: (sham) with ten animals. None of the animals presented post surgical complications being submitted to the optical tests at the 20th postoperative day. RESULTS: The analysis from the biospeckle tests, comparing the medians and standard deviations with T Student test, indicated that no significative difference was observed on the abdominal wall tissue activity in the four groups considered, with and without polypropylene mesh prosthesis implantation. CONCLUSION: The animal model is viable and the biospeckle open ways for a great number of experiments to be developed in evaluating tissue activity.(AU)

OBJETIVO: Avaliar o modelo experimental animal para o estudo da atividade tecidual da parede abdominal em sua interação com a prótese de polipropileno, através da utilização de um dos fenômenos ópticos da luz Laser, o biospeckle. MÉTODOS: Foram utilizados 50 ratos Wistar machos, divididos em quatro grupos: Grupo 1 com 10 animais não operados e controles; Grupo 2 com 10 animais submetidos a cirurgia sem a colocação de prótese; Grupo 3 com 20 animais submetidos a cirurgia com colocação de prótese de polipropileno pré-peritonial; Grupo 4 (Sham) com 10 animais. Nenhum animal apresentou complicações pós-operatórias, sendo que no 20º PO foram submetidos ao ensaio óptico. RESULTADOS: A comparação das médias e o desvio padrão das medidas da atividade tecidual da parede abdominal, com e sem implantação da prótese de polipropileno obtidas dos grupos de animais, pelo teste T de Student, não evidenciou diferença estatística significativa (p>0.05). CONCLUSÃO: A análise dos dados obtidos permitiu concluir que o modelo animal é viável e que o biospeckle abre caminhos para toda uma linha de experimentos a ser desenvolvida em avaliar atividade tecidual.(AU)