Platelet rich plasma to faster navel healing in lambs / Plasma rico em plaquetas para acelerar a cicatrização umbilical em cordeiros
Lucia Gonçalves Garcia Gazzetta, Sylvia; Chaves, Camila; Cavallaro Machado, Debora; Maria Roncato Duarte, Keila; Lopes Dias da Costa, Ricardo.
Bol. ind. anim. (Impr.);
71: 61-61, 2014.
Artigo
em Inglês
|
LILACS-Express
| ID: biblio-1466617
Resumo
Onfaloflebitis is common in lambs born in poor hygienic conditions and occurs where inadequate treatment of umbilical healing is placed. Males are more affected lambs probably because of contact with urine that slows healing umbilical and removes some medications or topical antibiotics applied facilitating the bacteria entrance, mainly Fusobacterium necrophorum affecting joints, lungs, kidneys, liver, leading to animal death. Platelets are blood cells that interact with several receptors and modulate platelet function. It promotes hemostasis through four mechanisms: adhesion, release of platelet secretion, aggregation and pro-coagulation action. Complex network of growth factors are involved in tissue homeostasis such as transforming growth factor (TGF)-b, platelet-derived growth factor (PDGF), insulin-like growth factor (IGF), fibroblast growth factor (FGF)-b and hepatocyte growth factor (HGF). These factors and other bioactive molecules are contained in platelet alpha granules, and the use of intra-articular injections of platelet concentrate has been proposed as a minimally invasive solution to promote cartilage, osteo and muscular healing. Its use in regenerative medicine represents a simple, low-cost, and minimally invasive approach that might fasten healing processes. Regenerative treatment with autologous products, including the PRP (Platelet Rich Plasma) have been widelO artigo não apresenta resumo em português.
Biblioteca responsável:
BR68.1
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